Molecular Biology

RESEARCH TOPICS

Tumour biology

• Molecular and functional analysis of diagnostic and therapeutic BIOMARKER

• Evaluation of potential biomarker in tumour tissue and liquid biopsies

Cancer stem cells

• Involvement in CHEMOTHERAPY RESISTANCE and the metastatic potential of tumours

DNA damage response

• Unravelling chemotherapeutic-related DNA repair mechanisms

• AGING tissue as cancer risk factor

Genome editing via CRISPR/Cas9 tools

• Precise knock-out in CANCER cell lines for functional analysis

• knock-in studies e.g. genomic tagging for live cell imaging

• gene activation studies using Cas9 activator

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