Fabian M. Commichau

Contact

Room 15.231

T +49 (0) 3573 85 915

Mail

Research interests

Bacterial physiology: amino acid and vitamin metabolism; characterization of proteins of unknown function; trigger enzymes; moonlighting proteins; enzymology; signal transduction; mechanisms of gene regulation; molecular evolution: mechanisms of genomic (in)stability in bacteria, evolution of novel metabolic pathways; communication of bacteria with their environment by second messenger signalling; pathogenic bacteria; Minibacillus: construction of a minimal organism. Identification of novel antibiotics that target synthesis of the essential second messenger c-di-AMP.

Education - professional positions

2019 - present, Full Professor at the BTU Cottbus-Senftenberg

2011 - 2019, Group leader, Dept. of General Microbiology, University of Göttingen

2018, Promotion to an Extraordinary Professor, University of Göttingen

2015, Habilitation “Microbiology”, University of Göttingen

2012, Visiting research scientist, Rijksuniversiteit Groningen, Netherlands

2009 - 2011, DSM Nutritional Products Ltd., Kaiseraugst, Switzerland

2008 - 2009, PostDoc with Prof. Guy R. Cornelis, University of Basel, Switzerland

2006 - 2008, PostDoc with Prof. Jörg Stülke, University of Göttingen

2003 - 2006, PhD student with Prof. Jörg Stülke, University of Göttingen

2003, Diploma degree “Diplom-Biologe“, Microbiology, RWTH Aachen

1997 - 2003, Studies of biology, RWTH Aachen University

Memberships

Memberships (VAAM (German Society for Microbiology), GASB (German Association for Synthetic Biology))

Editorial boards (Microbiology, Scientific ReportsMicrobial Physiology)

Talks

2020      Hohenheim University, 14.07.2020, „The human pathogen Listeria monocytogenes employs an essential signaling nucleotide to adapt to the environmental osmolarity“ (host: Prof. Schulze)

2019      Hannover University, 19.06.2019, “Bifunctional enzymes control a key metabolic intersection in a model bacterium” (host: Prof. Brüser)

2019      Vienna University, 05.06.2019, “Bifunctional enzymes control a key metabolic intersection in a model bacterium” (host: Prof. Wagner)

2019      Leipzig University, 09.04.2019, “Bifunctional enzymes control a key metabolic intersection in Bacillus subtilis” (host: Prof. Pompe)

2018      University Medical Center Göttingen, 04.07.2018, “A delicate connection in Gram-positive bacteria - c-di-AMP affects cell integrity by controlling osmolyte transport” (host: Prof. Lüder)

2018      Braunschweig University & DSMZ, 09.05.2018, “Harnessing bacterial underground metabolism for pathway development” (host: Prof. Jahn & Prof. Overmann).

2017      Mainz University, 29.11.2017, “A devil in disguise: a metabolic enzyme converts a transcriptional activator into a repressor” (host: Prof. Thines)

2017      Humboldt University Berlin, 24.10.2017, “A devil in disguise: a metabolic enzyme converts a transcriptional activator into a repressor” (host: Dr. Tschowri)

2017      Düsseldorf University/Forschungszentrum Jülich, 22.06.2017, “Adaptive evolution rewires Bacillus subtilis’metabolic network for vitamin B6 production” (host: Prof. Jaeger)

2017      Mainz University, 23.01.2017, “A complex between an enzyme and a transcription factor controls biosynthesis of the major metabolite glutamate in Bacillus subtilis” (host: Prof. Unden)

2017      BTU Cottbus-Senftenberg, 18.01.2017, “MiniBacillus – creation of a minimal organism for understanding life and industrial applications” (host: Prof. Stahmann)

2016      31. Symposium on Mechanisms of Gene Regulation, 28.-30.09.2016, Bad Bergzabern, “The Bacillus subtilis glutamate dehydrogenases RocG and GudB play a double game” (host: PD Dr. Brückner)

2016      Tübingen University, 02.06.2016, “Role of the essential signalling molecule cyclic di-AMP in maintaining the protective cell envelope in Listeria monocytogenes” (host: Prof. Forchhammer)

2016      Münster University, 03.03.2016, “Engineering Bacillus subtilis for vitamin B6 production uncovers genome flexibility and multiple promiscuous enzymes” (host: Prof. Fetzner)

2015      Namur University, 23.10.2015, “On pathways and evolution – glutamate homeostasis in Bacillus subtilis” (host: Dr. Renzi)

2015      Bielefeld University, 27.08.2015, “On pathways and evolution – glutamate homeostasis in Bacillus subtilis” (host: Prof. Noll)

2015      University Medical Center Göttingen, 06.05.2015, “Characterization of the Listeria monocytogenes diadenylate cyclase CdaA that produces the essential second messenger c-di-AMP” (host: Dr. Gunka)

2015      Jena University, 28.01.2015, “On pathways and evolution – glutamate homeostasis in Bacillus subtilis” (host: PD Dr. Brantl)

2014      Robert Koch Institute Wernigerode, 11.12.2014, “Biochemical and structural analysis of the essential diadenylate cyclase CdaA from Listeria monocytogenes” (host: Dr. Halbedel)

2014      Greifswald University, 17.07.2014, “On pathways and evolution – glutamate homeostasis in Bacillus subtilis” (host: Prof. Fesser)

2014      Marburg University, 24.04.2014, “Recovery of lost biochemical memory in Bacillus subtilis” (host: Prof. Bremer)

2013      Deutsches Zentrum für Luft- und Raumfahrtmedizin Köln, 07.05.2013, “Towards the full understanding of molecular processes essential for life of the model bacterium Bacillus subtilis” (host: Dr. Möller)

2012      Ulm University, 17.12.2012, “Bacillus subtilis responses to perturbation of glutamate homeostasis at the genome level” (host: Prof. Eikmanns)

2009      Erlangen University, 25.9.2009, BIGSS Summer School – Approaches to Molecular Biology (host: Prof. Hillen) 

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