Lipases at fluid interfaces

Lipases are enzymes (biocatalysts) that can selectively catalyze the cleavage of fats (triglycerides). Lipases share the following advantages with other enzymes: eco-efficient reaction conditions at atmospheric pressure, as well as activity in the solvent water and stability in organic solvents. These properties give lipases a high potential for industrial use. The main areas of application are the food and detergent industries, but they also play a central role in biocatalytic biodiesel production.

Successful use of lipases as interfacially active catalyst systems for the hydrolysis of native oils requires a fundamental understanding of the phenomena occurring at phase boundaries. To date, however, there is no comprehensive understanding of the processes at the interface.

The competitive behavior of the cleavage products produced by the lipase itself (fatty acids, partial glycerides) is of extraordinary importance for the conversion. As surface-active substances, these can drastically influence the course of the reaction and in some cases even bring it to a standstill.

The student research projects and theses within the scope of this project, are intended to make an important contribution to deepening our understanding of these processes.

The measurement methods used are mainly tensiometric methods (Pendant-Drop, Wilhelmy method). In special cases also ellipsometry, an optical method used only by a few groups worldwide for the investigation of fluid interfaces.

Since this is an interdisciplinary project, students will also come into contact with other research groups at this university as part of their work.

For detailed information on specific tasks, interested students are welcome to contact us personally.