Colloquium (virtuell)

Speaker: Prof. Dr. Gerd Kempermann German Center for Neurodegenerative Diseases (DZNE) Dresden and CRTD - Center for Regenerative Therapies, TU Dresden

Hosts: Prof. Dr. Notger Müller/Dr. Günter Peine University of Potsdam/Faculty of Health Sciences Brandenburg

Date: March 23, 2022, 5 p.m. Dial-in: https: //mhb-fontane.webex.com/meet/guenter.peine

As one of only two regions of the adult brain, the hippocampus produces new neurons throughout life that contribute to key hippocampal functions. "Adult neurogenesis" is an extraordinary form of plasticity: it allows for lifelong activity-dependent adaptation of the hippocampus to functional needs. This has implications for modern concepts of "neural reserve" and its importance for successful cognitive aging and lifestyle-dependent prevention of neurodegenerative diseases. Alzheimer's dementia, for example, affects the hippocampus early. A "neurogenic reserve" could increase hippocampal resilience and delay or even prevent disease sequelae.