Our basic research focuses on proteins or antibodies which are also of interest as pathomarkers. Therefore experimental work focuses mainly on overexpression of corresponding genes, purification of native or tagged proteins and modification of protein antigens in cells or reaction tubes. Antigenic properties of proteins are then analysed and antibodies raised against candidate proteins are produced and also purified for diagnostic applications which are studied in  cooperation with clinical partners.

Our intention is to channel newly discovered pathomarkers or established antigens optimized by protein modification into improved antigens and antibodies for multiparametric diacnostic or life science applications.

In summary, we understand this R&D aspect of our work as scouting for new pathomarkers in autoimmune diseases, tumor biology and in the future perhaps also in neurodegeneration and aging related diseases.