The "Cell Biology and Tissue Engineering" team focuses on research in the field of "Cell-Based Diagnostics and Therapy", a priority area of the Institute of Biotechnology at the Brandenburg University of Technology Cottbus-Senftenberg (BTU C-S, Campus Senftenberg) in the competence field of Life Sciences.
Our research activities are driven by 3D tissue models on a laboratory scale which are close to the natural situation. In contrast to the typical 2-dimensional (2D) cell culture technique, cells are cultivated in the laboratory in a 3D cell assembly in order to simulate the physiological situation in the body and to enable tissue-typical physiological behaviours of the cells.
Our research activities in the field of bone and cartilage focus on
- the in vitro engineering of cartilage tissue and its application in the personalized cell-based therapy of cartilage defects
- the generation of cartilage cell lines for the development of in vitro tissue test systems
- studies of the physiological activity of osteoclasts, especially in various diseases, and
- the development of cell-based diagnostic test systems of autoimmune diseases.
Currently, we are part of the joint research project "Consequences of age-associated cell and organ functions" of the Health Campus Brandenburg. Our project deals with the topic "Joint cartilage of elderly people - regeneration potential through body-own chondrocytes".
The programme of curricular teaching is closely connected with ongoing research activities and covers the basics of cell biology, cell biological methods, tissue engineering and the basics of different types of human tissue in theory (lecture, seminar) and practice (laboratory courses). Target groups for the courses offered by BTU C-S are currently the Bachelor and Master Degree Programs in Biotechnology.
Our research group also offers projects for Bachelor and Master Theses.