Publications from the previous 2 years
2026
Tumor-associated macrophages enhance peripheral nerve tumor infiltration and spinal cord repair. Dolci S, Mannino L, Rossi E, Bottani E, Ciarpella F, Piazza N, Karkossa I, Di Chio M, Savino B, Lucidi B, Pruonto G, Barone I, Campanelli A, Cersosimo F, Setten E, Gianoli S, Malik Z, Busetto G, Pezzotta A, Castagna A, Martinelli N, Ferretti S, Boschi F, Doherty A, Scupoli MT, Cavallini C, Malpeli G, Amenta A, Sagripanti L, Silani V, Cristofori P, Scanziani E, Sandri M, Pistocchi A, Bossolasco P, Endrizzi M, Schubert K, Fumagalli GF, Locati M, Bifari F, Decimo I.
Immunity. 2026 Feb 10;59(2):438-457.e16. doi: 10.1016/j.immuni.2025.12.016. Epub 2026 Jan 26.PMID: 41592573
2025
Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo. Rapöhn I, Broghammer H, Hoffmann A, Möhlis K, Moormann A, Kaczmarek I, Thor D, Großkopf H, Krieg L, Karkossa I, Schubert K, von Bergen M, Krause K, Breitfeld J, Kovacs P, Klöting N, Nuwayhid R, Langer S, Ghosh A, Wolfrum C, Stumvoll M, Blüher M, Heiker JT, Weiner J.Nat Commun. 2025 Dec 10;16(1):11075. doi: 10.1038/s41467-025-66950-y.
The ENDOMIX project: an interdisciplinary approach to understanding how real-life chemical mixtures target the immune system to trigger disease.Zenclussen AC, Belmar Erilkin V, Böhmert L, Borilova Linhartova P, Braeuning A, Braun G, Chevrier C, Duijts L, Escher BI, Felix J, Gómez-Olarte S, Guxens M, Herberth G, Hilscherova K, Klanova J, Kohl Y, Krischak K, Lagadic-Gossmann D, Langouët S, Llop S, Lopez-Espinosa MJ, Maitre L, Martin-Chouly C, Meyer N, Ouidir M, Pham TAM, Philippat C, Pieters R, Pinel-Marie ML, Podechard N, Polte T, Price E, Robinson O, Schubert K, Schumacher A, Stojanovska V, Tal T, Vineis P, van Vorstenbosch R, Vermeulen R, Warembourg C.Open Res Eur. 2025 Nov 21;4:271. doi: 10.12688/openreseurope.19088.2. eCollection 2024.
13C metabolic tracing in human SGBS cells provides a potential new approach methodology for assessing metabolism-disrupting properties of environmental chemicals. Goerdeler C, Engelmann B, Broghammer H, Aldehoff AS, Wabitsch M, Schubert K, Blüher M, Heiker JT, Rolle-Kampczyk U, von Bergen M.J Hazard Mater. 2025 Dec 5;500:140384. doi: 10.1016/j.jhazmat.2025.140384. Epub 2025 Nov 4.
Knock Out of miRNA-30a-5p and Reconstitution of the Actin Network Dynamics Partly Restores the Impaired Terminal Erythroid Differentiation during Blood Pharming.Thiel J, Sürün D, Brändle DC, Teichert M, Künzel SR, Friedrich U, Dahl A, Schubert K, Rzagalinski I, Shevchenko A, Traikov S, Mirtschink P, Wagenführ L, Buchholz F, Hölig K, Tonn T, Kronstein-Wiedemann R.Stem Cell Rev Rep. 2025 Nov;21(8):2637-2653. doi: 10.1007/s12015-025-10957-x. Epub 2025 Aug 26.
Advanced Proteomics Approaches Hold Potential for the Risk Assessment of Metabolism-Disrupting Chemicals as Omics-Based NAM: A Case Study Using the Phthalate Substitute DINCH. Aldehoff AS, Karkossa I, Broghammer H, Krupka S, Weiner J, Goerdeler C, Nuwayhid R, Langer S, Wabitsch M, Rolle-Kampczyk U, Klöting N, Blüher M, Heiker JT, von Bergen M, Schubert K.Environ Sci Technol. 2025 Aug 12;59(31):16193-16216. doi: 10.1021/acs.est.5c01206. Epub 2025 Jul 30.
How to Reproduce in the Siberian Winter: Proteome Dynamics Reveals the Timing of Reproduction-Related Processes in an Amphipod Species Endemic to Lake Baikal. Lipaeva P, Drozdova P, Vereshchagina K, Jakob L, Schubert K, Bedulina D, Luckenbach T.Ecol Evol. 2025 Jul 23;15(7):e71675. doi: 10.1002/ece3.71675. eCollection 2025 Jul.
The prognostic significance of HDL-associated apolipoproteins in ascitic fluid from patients with cirrhosis and spontaneous bacterial peritonitis. Murad M, Reuken PA, Schubert K, Reißing J, Ibidapo-Obe O, Große K, Frissen M, Haedge F, El-Hassani M, von Bergen M, Bruns T.Sci Rep. 2025 Jul 16;15(1):25714. doi: 10.1038/s41598-025-08238-1.
Serum proteomics of adults with acute liver failure provides mechanistic insights and attractive prognostic biomarkers. Remih K, Hufnagel FM, Karl AS, Durkalski-Mauldin V, Lee WM, Karvellas CJ, Su Z, Rule JA, Tomanová P, Krieg L, Karkossa I, Schubert K, von Bergen M, Tacke F, Luckhardt S, Ziegler N, Kannt A, Engel B, Taubert R, Fontana RJ, Strnad P; US Acute Liver Failure Study Group.JHEP Rep. 2025 Jan 30;7(5):101338. doi: 10.1016/j.jhepr.2025.101338. eCollection 2025 May.
Metabolic and molecular Characterization, following dietary exposure to DINCH, Reveals new Implications for its role as a Metabolism-Disrupting chemical. Krupka S, Aldehoff AS, Goerdeler C, Engelmann B, Rolle-Kampczyk U, Schubert K, Klöting N, von Bergen M, Blüher M.Environ Int. 2025 Feb;196:109306. doi: 10.1016/j.envint.2025.109306. Epub 2025 Jan 26.
2024
FGF21 and its underlying adipose tissue-liver axis inform cardiometabolic burden and improvement in obesity after metabolic surgery. Patt M, Karkossa I, Krieg L, Massier L, Makki K, Tabei S, Karlas T, Dietrich A, Gericke M, Stumvoll M, Blüher M, von Bergen M, Schubert K, Kovacs P, Chakaroun RM.EBioMedicine. 2024 Dec;110:105458. doi: 10.1016/j.ebiom.2024.105458. Epub 2024 Nov 27.
Proteomic analysis of extracellular vesicles derived from canine mammary tumour cell lines identifies protein signatures specific for disease state. Gutierrez-Riquelme T, Karkossa I, Schubert K, Liebscher G, Packeiser EM, Nolte I, von Bergen M, Murua Escobar H, Aguilera-Rojas M, Einspanier R, Stein T.BMC Vet Res. 2024 Oct 26;20(1):488. doi: 10.1186/s12917-024-04331-1.
Evaluating the performance of multi-omics integration: a thyroid toxicity case study. Canzler S, Schubert K, Rolle-Kampczyk UE, Wang Z, Schreiber S, Seitz H, Mockly S, Kamp H, Haake V, Huisinga M, Bergen MV, Buesen R, Hackermüller J.Arch Toxicol. 2025 Jan;99(1):309-332. doi: 10.1007/s00204-024-03876-2. Epub 2024 Oct 23.
A multidisciplinary perspective on the role of plastic pollution in the triple planetary crisis. Schmidt C, Kühnel D, Materić D, Stubenrauch J, Schubert K, Luo A, Wendt-Potthoff K, Jahnke A.Environ Int. 2024 Nov;193:109059. doi: 10.1016/j.envint.2024.109059. Epub 2024 Oct 9.
Dysregulated cytokine and oxidative response in hyper-glycolytic monocytes in obesity. Radushev V, Karkossa I, Berg J, von Bergen M, Engelmann B, Rolle-Kampczyk U, Blüher M, Wagner U, Schubert K, Rossol M.Front Immunol. 2024 Jul 10;15:1416543. doi: 10.3389/fimmu.2024.1416543. eCollection 2024.
The human intestinal bacterium Eggerthella lenta influences gut metabolomes in gnotobiotic mice. Viehof A, Haange SB, Streidl T, Schubert K, Engelmann B, Haller D, Rolle-Kampczyk U, von Bergen M, Clavel T.Microbiome Res Rep. 2024 Jan 18;3(2):14. doi: 10.20517/mrr.2023.65. eCollection 2024.
Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis. Aldehoff AS, Karkossa I, Goerdeler C, Krieg L, Schor J, Engelmann B, Wabitsch M, Landgraf K, Hackermüller J, Körner A, Rolle-Kampczyk U, Schubert K, von Bergen M.iScience. 2024 Apr 10;27(6):109711. doi: 10.1016/j.isci.2024.109711. eCollection 2024 Jun 21.
Metabolomics in human SGBS cells as new approach method for studying adipogenic effects: Analysis of the effects of DINCH and MINCH on central carbon metabolism. Goerdeler C, Engelmann B, Aldehoff AS, Schaffert A, Blüher M, Heiker JT, Wabitsch M, Schubert K, Rolle-Kampczyk U, von Bergen M.Environ Res. 2024 Jul 1;252(Pt 2):118847. doi: 10.1016/j.envres.2024.118847. Epub 2024 Apr 4.
Triclosan and its alternatives, especially chlorhexidine, modulate macrophage immune response with distinct modes of action. Raps S, Bahr L, Karkossa I, Rossol M, von Bergen M, Schubert K.Sci Total Environ. 2024 Mar 1;914:169650. doi: 10.1016/j.scitotenv.2023.169650. Epub 2023 Dec 29.