RESEARCH TOPICS
Tumour biology
• Molecular and functional analysis of diagnostic and therapeutic BIOMARKER
• Evaluation of potential biomarker in tumour tissue and liquid biopsies
Cancer stem cells
• Involvement in CHEMOTHERAPY RESISTANCE and the metastatic potential of tumours
DNA damage response
• Unravelling chemotherapeutic-related DNA repair mechanisms
• AGING tissue as cancer risk factor
Genome editing via CRISPR/Cas9 tools
• Precise knock-out in CANCER cell lines for functional analysis
• knock-in studies e.g. genomic tagging for live cell imaging
• gene activation studies using Cas9 activator