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Synthesis of mono Cytochrome P450 in a modified CHO-CPR cell-free protein production platform Author(s) Knauer, Jan Felix, Schulz, Christian, Zemella, Anne, Wüstenhagen, Doreen A., Walter, Ruben Magnus, Küpper, Jan-Heiner, Kubick, Stefan Type Scientific Article ref. Year of publication 2024 Multidisciplinary Source Scientific Reports Volume 14 ISSN 2045-2322 DOI https://doi.org/10.1038/s41598-024-51781-6
Morphology and Function of Red Blood Cells in COVID-19 Patients: Current Overview 2023 Author(s) Jung, Friedrich, Connes, Philippe Type Scientific Article ref. Year of publication 2024 COVID-19; SARS-CoV-2; red blood cell; deformation; aggregation; endothelial cell Source Life Volume 14 Issue/Journal number 4 ISSN 2075-1729 DOI https://doi.org/10.3390/life14040460
Novel high-resolution contrast agent ultrasound techniques HiFR CEUS and SR CEUSin combination with shear wave elastography, fat assessment and viscosity of liver parenchymal changes and tumors Author(s) Jung, E.M., Kaiser, U., Herr, W., Stroszczynski, C., Jung, F. Type Scientific Article ref. Year of publication 2024 Multimodal liver tissue imaging (M-Ref); UMA; HiFR CEUS; SR CEUS; Elastography; Fat evaluation; Viscosity Source Clinical Hemorheology and Microcirculation, S. 263 - 273 Volume 86 (2024) URL https://content.iospress.com/download/clinical-hemorheology-and-microcirculation/ch249103?id=clinical-hemorheology-and-microcirculation%2Fch249103 DOI https://doi.org/10.3233/CH-249103
Finding possible diagnostic markers for differentiating benign and malignant thyroid tumors on example investigate of rheological properties Author(s) Javakhishvili, I, Sanikidze, T, Mardaleishvili, K, Momtselidze, N, Urdulashvili, T, Mantskava, M, Prantl, L, Jung, F Type Scientific Article ref. Year of publication 2024 Thyroid gland; Rheology; Oncology Source Clinical Hemorheology and Microcirculation, S. 515 - 526 Volume 87 (2024) Issue/Journal number 4 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch249102 DOI https://doi.org/10.3233/CH-249102
Tirzepatide and exercise training in obesity Author(s) Bagherzadeh-Rahmani, B, Marzetti, E, Karami, E, Campbell, BI, Fakourian, A, Haghighi, AH, Mousavi, SH, Heinrich, KM, Brazzi, L, Jung, F, Baker, JS, Patel, DI Type Scientific Article ref. Year of publication 2024 Obesity; Combined training; GIP; GLP-1; Tirzepatide Source Clinical Hemorheology and Microcirculation, S. 465 - 480 Volume 87 (2024) Issue/Journal number 4 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch242134 DOI https://doi.org/10.3233/CH-242134
Smart scanning: automatic detection of superficially located lymph nodes using ultrasound – initial results Author(s) Rink, M, Künzel, J, Strosczynski, C, Jung, F, Jung, EM Type Scientific Article ref. Year of publication 2024 Artificial intelligence; Ultrasound; Multimodal ultrasound; Lymphatic; Lymph node ultrasound; Technical aspects Source Fortschr RöntgenstrFortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, S. 1 - 7 Volume 2024 URL https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2331-0951.pdf DOI https://doi.org/10.1055/a-2331-0951
Study of some components of the influence and formation of blood flow in patients with “slow flow” Author(s) Gogilashvili, N, Tsinamdzgvrishvili, B, Momtselidze, N, Jung, F, Prantl, L, Urdulashvili, T, Mantskava, M Type Scientific Article ref. Year of publication 2024 Slow flow; Aggregation; Deformation; Coagulation/anticoagulation; In silico blood rheological index; Plasma viscosity Source Clinical Hemorheology and Microcirculation, S. 325 - 336 Volume 88 (2024) Issue/Journal number 3 URL https://journals.sagepub.com/doi/epub/10.3233/CH-249104 DOI https://doi.org/10.3233/CH-249104
Cuproptosis and physical training Author(s) Kordi, N, Saydi, A, Azimi, M, Mazdarani, F, Gadruni, K, Jung, F, Karami, S Type Scientific Article ref. Year of publication 2024 Copper; Exercise; Cell death; Physical activity; Cuproptosis Source Clinical Hemorheology and Microcirculation, S. 337 - 350 Volume 88 (2024) Issue/Journal number 3 URL https://journals.sagepub.com/doi/epub/10.3233/CH-242329 DOI https://doi.org/10.3233/CH-242329
Modulation of pulmonary oxidative status in methamphetamine-withdrawn rats, comparing the effects of continuous training and NBS superfood supplementation Author(s) Saydi, A, Behpoor, N, Khamis Abadi, F, Jung, F, Kordi, N Type Scientific Article ref. Year of publication 2024 Nrf2; NOX4; MDA; SOD; Lung; Nutrition Bio-shield Source Clinical Hemorheology and Microcirculation, S. 373 - 384 Volume 88 (2024) Issue/Journal number 3 URL https://journals.sagepub.com/doi/epub/10.3233/CH-242306 DOI https://doi.org/10.3233/CH-242306
PANoptosis and cardiovascular disease: The preventive role of exercise training Author(s) Kordi, N, Sanaei, M, Akraminia, P, Yavari, S, Saydi, A, Abadi, FK, Heydari, N, Jung, F, Karami, S Type Scientific Article ref. Year of publication 2024 PANoptosis; Pyroptosis; Apoptosis; Necroptosis; Activity; Training Source Clinical Hemorheology and Microcirculation, S. 499 - 512 Volume 88 (2024) Issue/Journal number 4 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch242396 DOI https://doi.org/10.3233/CH-242396
Dynamic Contrast Ultrasound Diagnostics (CEUS) of Liver Lesions and Post-treatment Control with A New High-resolution Examination Technique (HiFR) and Perfusion Author(s) Jung, EM, Pleyer, L, Dropco, I, Kaiser, U, Yi, D, Stroszczynski, C, Jung, F Type Scientific Article ref. Year of publication 2024 Ultrasound contrast media; Magnetic resonance imaging; Contrast-enhanced ultrasound; Liver analysis; Perfusion Source Journal of Gastrointestinal & Liver Diseases, S. 362 - 371 Volume 33 Issue/Journal number 3 DOI https://doi.org/10.15403/jgld-5589
Ferroptosis and aerobic training in ageing Author(s) Kordi, Negin, Saydi, Ali, Karami, Sajad, Bagherzadeh-Rahmani, Behnam, Marzetti, Emanuele, Jung, Friedrich, Stockwell, Brent R. Type Scientific Article ref. Year of publication 2024 Aerobic training; Elderly; Iron metabolism; Amino acid metabolism; Lipid metabolism Source Clinical Hemorheology and Microcirculation, S. 347 - 366 Volume 87 (2024) Issue/Journal number 3 DOI https://doi.org/10.3233/CH-232076
History of the cutaneous microcirculation from antiquity to modern times Author(s) Jung, Friedrich Type Scientific Article ref. Year of publication 2024 Human; Cutaneous; Capillary circulation; Microcirculation Source Clinical Hemorheology and Microcirculation, S. 29 - 50 Volume 86 (2024) Issue/Journal number 1-2 DOI https://doi.org/10.3233/CH-248001
Impact of different severity hyperglycemia on erythrocyte rheological properties Author(s) Mantskava, M, Chkhitauri, L, Shekiladze, E, Tskhvediani, N, Kalmakhelidze, S, Momtselidze, N, Prantl, L, Jung, F, Machalinski, B, Wojciech, P, Sanikidze, T Type Scientific Article ref. Year of publication 2024 Hyperglycemia; Erythrocyte; Band 3 protein; Oxidative stress; Osmotic resistance Source Clinical Hemorheology and Microcirculation, S. 271 - 281 Volume 87 (2024) Issue/Journal number 2 URL https://journals.sagepub.com/doi/epub/10.3233/CH-239104 DOI https://doi.org/10.3233/CH-239104
Initial experiences with dynamic, quality indicator-based multimodal tissue analysis (M-Ref) with parallel assessment of viscosity and shear wave elastography in liver parenchyma alterations Author(s) Jung, EM, Wiesinger, I, Kaiser, U, Jung, F Type Scientific Article ref. Year of publication 2024 Source Clinical Hemorheology and Microcirculation, S. 419 - 427 Volume 88 Issue/Journal number 4 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch248111 DOI https://doi.org/10.3233/CH-248111
Contrast-enhanced intraoperative ultrasound shows excellent performance in improving intraoperative decision-making Author(s) Kupke, Laura S., Dropco, Ivor, Götz, Markus, Kupke, Paul, Jung, Friedrich, Stroszczynski, Christian, Jung, Ernst Michael Editor(s) Miraglia, Roberto Type Scientific Article not ref. Publisher name MDPI ultrasound; contrast-enhanced ultrasound; CEUS; micro-vascularization; intraoperative ultrasound; IOUS; intraoperative decision-making Source Life Volume 14 Issue/Journal number 9 ISSN 2075-1729 DOI https://doi.org/10.3390/life14091199
Initial description of the novel handheld wireless ultrasound device TE Air with Doppler and Color Duplex imaging Author(s) Jung, Ernst Michael, Jung, Friedrich, Dong, Yi, Kaiser, Ulrich Type Scientific Article ref. Year of publication 2024 Mindray; handheld ultrasound; TE Air; ultrasound; point-of-care ultrasound Source Clinical Hemorheology and Microcirculation, S. 89 - 97 Volume 86 Issue/Journal number 1-2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch238100 DOI https://doi.org/10.3233/CH-238100
First assessment of flow phenomena of acute and chronic thrombosis in the jugular veins using new ultrasound vector-flow imaging Author(s) Luderer, V., Jung, Friedrich, Brandenstein, M., Stroszczynski, Christian, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2024 Thrombosis; vector-flow-imaging; high resolution ultrasound; color-coded duplex sonography Source Clinical Hemorheology and Microcirculation, S. 133 - 142 Volume 86 Issue/Journal number 1-2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch238117 DOI https://doi.org/10.3233/CH-238117
In vitro simulation of the liver first-pass effect with biotransformation-competent HepG2 cells to study effects of MG-132 on liver and cancer cells Author(s) Kammerer, Sarah, Nowak, Elisabeth, Mantke, René, Jung, Friedrich, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2024 Liver biotransformation; first-pass effect; CYP3A4; MG-132; cancer cells; in vitro culture systems Source Clinical Hemorheology and Microcirculation, S. 159 - 168 Volume 86 Issue/Journal number 1-2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch238108 DOI https://doi.org/10.3233/CH-238108
Effects of arthrospira platensis on human Uumbilical vein endothelial cells Author(s) Krüger-Genge, Anne, Harb, Kudor, Braune, Steffen, Jung, Conrad H. G., Westphal, Sophia, Bär, Stefanie, Mauger, Olivia, Küpper, Jan-Heiner, Jung, Friedrich Editor(s) Georgianos, Panagiotis Type Scientific Article not ref. Publisher name MDPI human umbilical vein endothelial cells; HUVEC Source Life Volume 14 Issue/Journal number 10 ISSN 2075-1729 DOI https://doi.org/10.3390/life14101253
Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4 Author(s) Rosellini, Matteo, Omer, Ejlal A., Schulze, Alicia, Ali, Nadeen T., Boulos, Joelle C., Marini, Federico, Küpper, Jan-Heiner, Efferth, Thomas Type Scientific Article not ref. Publisher name Springer Berlin Heidelberg Cytotoxicity; Ecotoxicity; Environmental pollution; Hepatotoxicity; Marine pollution; Microplastic; RNA-sequencing; Biological Sciences Source Archives of Toxicology, S. 525 - 536 Volume 98 Issue/Journal number 2 ISSN 0340-5761 1432-0738 DOI https://doi.org/10.1007/s00204-023-03648-4
OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects Author(s) Haas, Manuel, Ackermann, Gabriel, Küpper, Jan-Heiner, Glatt, Hansruedi, Schrenk, Dieter, Fahrer, Jörg Type Scientific Article ref. Year of publication 2023 Pyrrolizidine alkaloids; Cytotoxicity; Genotoxicity; OCT1; Transport; Primary human hepatocytes; γH2AX; p53 Source Archives of Toxicology, S. 3259 - 3271 Volume 97 Issue/Journal number 12 ISSN 1432-0738 0340-5761 URL https://link.springer.com/article/10.1007/s00204-023-03591-4 DOI https://doi.org/10.1007/s00204-023-03591-4
Stable Chinese Hamster Ovary Suspension Cell Lines Harboring Recombinant Human Cytochrome P450 Oxidoreductase and Human Cytochrome P450 Monooxygenases as Platform for In Vitro Biotransformation Studies Author(s) Schulz, Christian, Herzog, Natalie, Kubick, Stefan, Jung, Friedrich, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2023 Chinese hamster ovary cells; CHO-K1; CPR; CYP450; cytochrome P450 monooxygenase; liver; NADPH P450 oxidoreductase; phase-1 biotransformation; serum-free; suspension cells Source Cells Volume 12 Issue/Journal number 17 ISSN 2073-4409 URL https://www.mdpi.com/2073-4409/12/17/2140#metrics DOI https://doi.org/10.3390/cells12172140
Anti-Cancer Prodrug Cyclophosphamide Exerts Thrombogenic Effects on Human Venous Endothelial Cells Independent of CYP450 Activation—Relevance to Thrombosis Author(s) Krüger-Genge, Anne, Köhler, Susanne, Laube, Markus, Haileka, Vanessa, Lemm, Sandy, Majchrzak, Karolina, Kammerer, Sarah, Schulz, Christian, Storsberg, Joachim, Pietzsch, Jens, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2023 cancer; cyclophosphamide; human umbilical vein endothelial cells; HUVEC; liver; cytochrome P450 enzymes (CYP); thrombosis Source Cells Volume 12 Issue/Journal number 15 ISSN 2073-4409 URL https://www.mdpi.com/2073-4409/12/15/1965 DOI https://doi.org/10.3390/cells12151965
Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery Author(s) Haas, Manuel, Wirachowski, Karina, Thibol, Lea, Küpper, Jan-Heiner, Schrenk, Dieter, Fahrer, Jörg Type Scientific Article ref. Year of publication 2023 Cytotoxicity; Genotoxicity; Benchmark dose modeling; Pyrrolizidine alkaloids; Primary human hepatocytes; Potency ranking; γH2AX; p53; DNA damage Source Archives of Toxicology, S. 1413 - 1428 Volume 97 Issue/Journal number 5 ISSN 0340-5761 URL https://link.springer.com/article/10.1007/s00204-023-03482-8 DOI https://doi.org/10.1007/s00204-023-03482-8
Light-induced changes in the morphology and fluorescence of Arthrospira platensis Author(s) Jung, Conrad H. G., Waldeck, Peter, Petrick, Ingolf, Akinwunmi, Mosunmol, Braune, Steffen, Jung, Friedrich, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2023 Arthrospira platensis; light stress; photoinhibition; phototoxicity; morphology; fluorescence Source Clinical Hemorheology and Microcirculation, S. 71 - 77 Volume 9 Issue/Journal number 1 ISSN 1386-0291 URL https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb239001 DOI https://doi.org/10.3233/JCB-239001
Current aspects of multimodal ultrasound liver diagnostics using contrast-enhanced ultrasonography (CEUS), fat evaluation, fibrosis assessment, and perfusion analysis – An update Author(s) Jung, Ernst Michael, Dong, Yi, Jung, Friedrich Type Scientific Article ref. Year of publication 2023 Contrast enhanced ultrasonography (CEUS); fibrosis; perfusion analysis; liver cancer Source Clinical Hemorheology and Microcirculation, S. 181 - 193 Volume 83 Issue/Journal number 2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch239100 DOI https://doi.org/10.3233/CH-239100
Parallel study of the rheological status, vascular changes and intracardiac hemodynamics in heart failure in coronary artery disease Author(s) Mantskava, Maia, Jung, Friedrich, Sanikidze, Tamar, Momtselidze, Nana Type Scientific Article ref. Year of publication 2023 RBC; aggregation; deformation; viscosity; resistance arteries Source Clinical Hemorheology and Microcirculation, S. 185 - 192 Volume 84 Issue/Journal number 2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch231744 DOI https://doi.org/10.3233/CH-231744
Advanced multimodal imaging of solid thyroid lesions with artificial intelligence-optimized B-mode, elastography, and contrast-enhanced ultrasonography parametric and with perfusion imaging: Initial results Author(s) Jung, Ernst Michael, Stroszczynski, Christian, Jung, Friedrich Type Scientific Article ref. Year of publication 2023 Thyroid lesions; multimodal ultrasound; artificial intelligence (AI); UMA-elastography; contrast enhanced ultrasonography (CEUS); parametric-perfusion analysis Source Clinical Hemorheology and Microcirculation, S. 227 - 236 Volume 84 Issue/Journal number 2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch239102 DOI https://doi.org/10.3233/CH-239102
Cardiac rehabilitation in coronary artery bypass grafting patients: Effect of eight weeks of moderate-intensity continuous training versus high-intensity interval training Author(s) Shafiee, Neda, Kordi, Negin, Gadruni, Keivan, SalehFard, Ziba, Jung, Friedrich, Heidari, Naser Type Scientific Article ref. Year of publication 2023 Training; angiogenesis; cardiovascular; endostatin; pro-adrenomedullin Source Clinical Hemorheology and Microcirculation, S. 305 - 314 Volume 83 Issue/Journal number 3 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch221605 DOI https://doi.org/10.3233/CH-221605
Color mapping using ultrasound system-integrated perfusion software for evaluation of focal liver lesions: a possible first step for more independent reading Author(s) Dropco, Ivor, Kaiser, Ulrich, Wagner, Lola, Brunner, Stefan M., Schlitt, Hans Jürgen, Stroszczynski, Christian, Jung, Friedrich, Yi, Dong, Herr, Wolfgang, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2023 CEUS; parametric imaging; dynamic vascularization; liver malignancies Source Journal of Gastrointestinal and Liver Diseases, S. 479 - 487 Volume 32 Issue/Journal number 4 ISSN 1842-1121 URL https://europepmc.org/article/med/38147619 DOI https://doi.org/10.15403/jgld-4997
The effect of plastic-related compounds on transcriptome-wide gene expression on CYP2C19-overexpressing HepG2 cells Author(s) Rosellini, Matteo, Schulze, Alicia, Omer, Ejlal A., Ali, Nadeen T., Marini, Federico, Küpper, Jan-Heiner, Efferth, Thomas Type Scientific Article ref. Year of publication 2023 cytotoxicity; ecotoxicity; hepatotoxicity; microplastic; RNA sequencing Source Molecules Volume 28 Issue/Journal number 16 ISSN 1420-3049 URL https://www.mdpi.com/1420-3049/28/16/5952 DOI https://doi.org/10.3390/molecules28165952
Response of Arthrospira platensis to different temperatures regarding growth and biochemical composition Author(s) Nghinaunye, Theopolina, Waldeck, Peter, Jung, Conrad H. G., Küpper, Jan-Heiner, Jung, Friedrich, Braune, Steffen Type Scientific Article ref. Year of publication 2023 Arthrospira platensis; growth; temperature; bioreactor Source Clinical Hemorheology and Microcirculation, S. 1 - 7 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch238104 DOI https://doi.org/10.3233/CH-238104
Decarbonization of Arthrospira platensis production by using atmospheric CO2 as an exclusive carbon source: proof of principle Author(s) Jung, Conrad H. G., Nghinaunye, Theopolina, Waldeck, Peter, Braune, Steffen, Petrick, Ingolf, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2023 Arthrospira platensis; Atmospheric CO2; Biomass production; Climate change; Carbon capturing; Decarbonization Source International Journal of Environmental Science and Technology ISSN 1735-2630 URL https://link.springer.com/article/10.1007/s13762-023-05215-x#citeas DOI https://doi.org/10.1007/s13762-023-05215-x
Long-term aerobic exercise training in type two diabetic patients alters the expression of miRNA-223 and its corresponding target, the P2RY12 receptor, attenuating platelet function Author(s) Taghizadeh, Mahmoudreza, Mehdi, Kargarfard, Braune, Steffen, Jung, Friedrich, Mahmood, Naderi Type Scientific Article ref. Year of publication 2022 Exercise training; diabetes; microRNA-223; P2RY12 receptor; Insulin resistance; platelet Source Clinical Hemorheology and Microcirculation, S. 107 - 116 Volume 80 Issue/Journal number 2 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch211209 DOI https://doi.org/10.3233/CH-211209
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter Author(s) Vagiannis, Dimitrios, Zhang, Yu, Budagaga, Youssif, Novotna, Eva, Skarka, Adam, Kammerer, Sarah, Küpper, Jan-Heiner, Hofman, Jakub Type Scientific Article ref. Year of publication 2022 Source Toxicology and Applied Pharmacology Volume Vol. 434 ISSN 0041-008X DOI https://doi.org/10.1016/j.taap.2021.115823
Surface imaging of breast implants using modern high-frequency ultrasound technology in comparison to high-end sonography with power analyses for B-scan optimization Author(s) Diesch, S. T., Jung, Friedrich, Prantl, Lukas, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 487 - 495 Volume 80 Issue/Journal number 4 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-219204
Dynamic endoluminal contrast enhanced ultrasound (CEUS) for display of drainages in inflammatory abdominal fluid collections Author(s) Jung, Ernst Michael, Jung, Friedrich, Stroszczynski, Christian, Wiesinger, Isabel Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 49 - 59 Volume 80 Issue/Journal number 2 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-211370
An Inverse Shape-Memory Hydrogel Scaffold Switching Upon Cooling in a Tissue-Tolerated Temperature Range Author(s) Tartivel, Lucile, Blocki, Anna M., Braune, Steffen, Jung, Friedrich, Behl, Marc, Lendlein, Andreas Type Scientific Article ref. Year of publication 2022 Source Advanced materials interfaces Volume 9 Issue/Journal number 6 ISSN 2196-7350 DOI https://doi.org/10.1002/admi.202101588
Primary-like Human Hepatocytes Genetically Engineered to Obtain Proliferation Competence as a Capable Application for Energy Metabolism Experiments in In Vitro Oncologic Liver Models Author(s) Scheffschick, Andrea, Babel, Jonas, Sperling, Sebastian, Nerusch, Julia, Herzog, Natalie, Seehofer, Daniel, Damm, Georg Type Scientific Article ref. Year of publication 2022 upcyte hepatocytes; primary human hepatocytes; HepG2 cells; HCC; energy metabolism Source Biology Volume 11 Issue/Journal number 8 ISSN 2079-7737 DOI https://doi.org/10.3390/biology11081195
Differential sensitivity of assays for determining vein endothelial cell senescence Author(s) Lau, S., Gossen, Maike, Lendlein, Andreas, Jung, Friedrich Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 191 - 203 Volume 81 Issue/Journal number 3 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-211294
Modified contrast-enhanced ultrasonography with the new high-resolution examination technique of high frame rate contrast-enhanced ultrasound (HiFR-CEUS) for characterization of liver lesions: First results Author(s) Jung, Ernst Michael, Moran, Valentina Ocañaa, Engel, Martin, Krüger-Genge, Anne, Stroszczynski, Christian, Jung, Friedrich Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 1 - 16 ISSN 1875-8622 DOI https://doi.org/10.3233/CH-221449
Influence of Different Light-Emitting Diode Colors on Growth and Phycobiliprotein Generation of Arthrospira platensis Author(s) Jung, Conrad H. G., Waldeck, Peter, Sykora, Shadi, Braune, Steffen, Petrick, Ingolf, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2022 Source Life Volume 12 Issue/Journal number 6 ISSN 2075-1729 DOI https://doi.org/10.3390/life12060895
High resolution flow with glazing flow for optimized flow detection in transjugular intrahepatic portosystemic stent shunt (TIPS): First results Author(s) Jung, Ernst Michael, Jung, Friedrich, Verloh, Niklas, Haimerl, Michael, Lürken, Lukas, Jage, Simon, Stroszczynski, Christian, Scharf, Gregor Type Scientific Article ref. Year of publication 2022 Source Clinical hemorheology and microcirculation, S. 231 - 238 Volume 82 Issue/Journal number 3 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-221427
Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines Author(s) Lemm, Sandy, Köhler, Susanne, Wodtke, Robert, Jung, Friedrich, Küpper, Jan-Heiner, Pietzsch, Jens, Laube, Markus Type Scientific Article ref. Year of publication 2022 Source Cells Volume 11 Issue/Journal number 15 ISSN 2073-4409 DOI https://doi.org/10.3390/cells11152447
Lipophilic and Hydrophilic Compounds from Arthrospira platensis and Its Effects on Tissue and Blood Cells—An Overview Author(s) Jung, Friedrich, Braune, Steffen, Jung, Conrad H. G., Krüger-Genge, Anne, Waldeck, Peter, Petrick, Ingolf, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2022 Source Life Volume 12 Issue/Journal number 10 ISSN 2075-1729 DOI https://doi.org/10.3390/life12101497
A.L. Copley Best Paper Prize 2021 Author(s) Jung, Friedrich, Connes, Philippe, Lehmann, Christian Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 199 - 200 Volume 82 Issue/Journal number 3 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-229901
Effects of Arthrospira platensis-derived substances on blood cells Author(s) Braune, Steffen, Krüger-Genge, Anne, Köhler, S., Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 315 - 321 Volume 85(2023) Issue/Journal number 3 ISSN 1875-8622 DOI https://doi.org/10.3233/CH-229103
Post-mortem distribution of Iodinated Contrast Media (ICM) (iodixanol versus iopromide) in the porcine kidney after multiple bolus injections in vivo into the supra-renal aorta Author(s) Jung, Friedrich, Lamby, Philipp, Prantl, Lukas, Wiggermann, P., Jung, Ernst Michael, Krüger-Genge, Anne, Franke, Ralf-Peter Type Scientific Article ref. Year of publication 2022 Source Clinical Hemorheology and Microcirculation, S. 289 - 295 Volume 85(2023) Issue/Journal number 3 ISSN 1875-8622 DOI https://doi.org/10.3233/CH-229102
Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells Author(s) Abdelfatah, Sara, Nass, Janine, Knorz, Caroline, Klauck, Sabine M., Küpper, Jan-Heiner, Efferth, Thomas Type Scientific Article ref. Year of publication 2022 Source Cell biology and toxicology, S. 325 - 345 Volume 38 Issue/Journal number 2 ISSN 1573-6822 0742-2091 DOI https://doi.org/10.1007/s10565-021-09599-9
Enabling insights into the cytochrome P450 isoform specific metabolism of radiotracers by CYP overexpressing hepatoblastoma cell lines Author(s) Lemm, Sandy, Köhler, Susanne, Wodtke, Robert, Jung, Friedrich, Küpper, Jan-Heiner, Pietzsch, Jens, Laube, Markus Type Scientific Article ref. Year of publication 2022 Source Nuclear Medicine and Biology, S. 66 - 67 Issue/Journal number 108-109, Supplement ISSN 1872-9614
The chemical structure impairs the intensity of genotoxic effects promoted by 1,2-unsaturated pyrrolizidine alkaloids in vitro Author(s) Buchmueller, Julia, Enge, Anne-Margarethe, Peters, Antonia, Ebmeyer, Johanna, Küpper, Jan-Heiner, Schäfer, Bernd, Bräuning, Albert, Hessel-Pras, Stefanie Type Scientific Article ref. Year of publication 2022 Source Food and Chemical Toxicology Volume Vol. 164 ISSN 1873-6351 0278-6915 DOI https://doi.org/10.1016/j.fct.2022.113049
Intraoperative contrast-enhanced ultrasound can have a crucial role in surgical decision-making during hepato-pancreatico-biliary surgery –Analysis of impact and input Author(s) Werner, Jens Martin, Zidek, Martin, Kammerer, Sylvia, Platz Batista da Silva, Natascha, Jung, Friedrich, Schlitt, Hans Jürgen, Hornung, Matthias, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2021 Surgical decision-making; hepato-pancreatico-biliary surgery; CEUS; elastography Source Clinical Hemorheology and Microcirculation, S. 1 - 14 Volume 78 Issue/Journal number 1 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch201031 DOI https://doi.org/10.3233/CH-201031
Arthrospira platensis accelerates the formation of an endothelial cell monolayer and protects against endothelial cell detachment after bacterial contamination Author(s) Krüger-Genge, Anne, Steinbrecht, Susanne, Jung, Conrad H. G., Westphal, Sophia, Klöpzig, Stefanie, Waldeck, Peter, Küpper, Jan-Heiner, Storsberg, J., Jung, Friedrich Type Scientific Article ref. Year of publication 2021 Arthrospira platensis; endothelial cells; xCELLigence system Source Clinical Hemorheology and Microcirculation, S. 151 - 161 Volume 78 Issue/Journal number 2 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch201096 DOI https://doi.org/10.3233/CH-201096
A.L. Copley Best Paper Prize 2020 Author(s) Jung, Friedrich, Connes, Philippe, Lehmann, Christian Type Scientific Article ref. Year of publication 2021 Source Clinical Hemorheology and Microcirculation, S. 245 - 246 Volume 77 Issue/Journal number 3 ISSN 1875-8622 1386-0291 URL https://europepmc.org/article/med/33720877 DOI https://doi.org/10.3233/ch-219001
Potential Effects of Nonadherent on Adherent Human Umbilical Venous Endothelial Cells in Cell Culture Author(s) Schulz, Christian, Krüger-Genge, Anne, Lendlein, Andreas, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2021 human venous endothelial cells; adherent; non-adherent; viability; mediator release Source International Journal of Molecular Science Volume 22 Issue/Journal number 3 URL https://www.mdpi.com/1422-0067/22/3/1493 DOI https://doi.org/10.3390/ijms22031493
The influence of pulsed electromagnetic field therapy (PEMFT) on cutaneous blood flow in healthy volunteers Author(s) Biermann, Niklas, Sommerauer, Laura, Diesch, Sophia, Koch, Christoph, Jung, Friedrich, Kehrer, Andreas, Prantl, Lukas, Taeger, Christian D. Type Scientific Article ref. Year of publication 2021 Pulsed electromagnetic field therapy (PEMFT); microcirculation; cutaneous blood flow Source Clinical Hemorheology and Microcirculation, S. 495 - 501 Volume 76 Issue/Journal number 4 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209224 DOI https://doi.org/10.3233/CH-209224
Interstitial lung opacities in patients with severe COVID-19 pneumonia by bedside high-resolution ultrasound in association to CO2 retention Author(s) Peschel, G., Jung, Ernst Michael, Fisser, C., Putz, F. J., Wertheimer, T., Sinner, B., Lunz, D., Jung, Friedrich, Müller, M. Type Scientific Article ref. Year of publication 2021 Source Clinical Hemorheology and Microcirculation, S. 355 - 365 Volume 77 Issue/Journal number 4 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch200925 DOI https://doi.org/10.3233/CH-200925
Contrast-enhanced ultrasound (CEUS) and perfusion imaging using VueBox® Author(s) Wiesinger, Isabel, Jung, Friedrich, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2021 Source Clinical Hemorheology and Microcirculation Volume 78 Issue/Journal number 1 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch201040 DOI https://doi.org/10.3233/CH-201040
The metabolic pattern of hepatotoxic pyrrolizidine alkaloids in liver cells Author(s) Geburek, Ina, Rutz, Lukas, Gao, Lan, Küpper, Jan-Heiner, These, Anja, Schrenk, Dieter Type Scientific Article ref. Year of publication 2021 Source Chemical Research in Toxicology, S. 1101 - 1113 Volume 34 Issue/Journal number 4 URL https://pubs.acs.org/doi/abs/10.1021/acs.chemrestox.0c00507 DOI https://doi.org/10.1021/acs.chemrestox.0c00507
Bioreactor for the cultivation of Arthrospira platensis under controlled conditions Author(s) Jung, Conrad H. G., Waldeck, Peter, Petrick, Ingolf, Braune, Steffen, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2021 Source Journal of Cellular Biotechnology, S. 35 - 40 Volume 7 Issue/Journal number 1 URL https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb210032 DOI https://doi.org/10.3233/JCB-210032
Phycocyanin from Arthrospira platensis as Potential Anti-Cancer Drug: Review of In Vitro and In Vivo Studies Author(s) Braune, Steffen, Krüger-Genge, Anne, Kammerer, Sarah, Jung, Friedrich, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2021 Source Life, S. 91 Volume 11 Issue/Journal number 2 URL https://www.mdpi.com/2075-1729/11/2/91 DOI https://doi.org/10.3390/life11020091
Three-Dimensional Liver Culture Systems to Maintain Primary Hepatic Properties for Toxicological Analysis In Vitro Author(s) Kammerer, Sarah Type Scientific Article ref. Year of publication 2021 Source International Journal of Molecular Sciences Volume 22 Issue/Journal number 19 ISSN 1422-0067 DOI https://doi.org/10.3390/ijms221910214
High resolution flow (HR Flow) and Glazing Flow in cases of hepatic flow changes: Comparison to color-coded doppler sonography (CCDS) Author(s) Jung, Ernst Michael, Kammerer, Sarah, Brandenstein, M., Putz, F. J., Stroszczynski, Christian, Jung, Friedrich Type Scientific Article ref. Year of publication 2021 Liver vascular imaging; high resolution flow (HR); Glazing Flow; imaging quality; artefact reduction Source Clinical Hemorheology and Microcirculation, S. 3 - 17 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch219102 DOI https://doi.org/10.3233/CH-219102
Quantification of dynamic contrast-enhanced ultrasound (CEUS) in non-cystic breast lesions using external perfusion software Author(s) Jung, Ernst Michael, Jung, Friedrich, Stroszczynski, Christian, Wiesinger, Isabel Type Scientific Article ref. Year of publication 2021 Source Scientific Reports Volume 11 ISSN 2045-2322 URL https://www.nature.com/articles/s41598-021-96137-6 DOI https://doi.org/10.1038/s41598-021-96137-6
Differences in human and minipig platelet number, volume and activation induced by borosilicate glass beads in a modified chandler loop-system Author(s) Greif, G., Mrowietz, Christof, Wendt, M., Jung, Friedrich, Hiebl, Bernhard, Meyer-Sievers, H. Type Scientific Article ref. Year of publication 2021 Pig; minipig; platelet activation; platelet count; platelet volume; FACS; monoclonal antibody; CD42; CD61; CD62P; CD63 Source Clinical Hemorheology and Microcirculation, S. 149 - 155 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch219201 DOI https://doi.org/10.3233/CH-219201
Effect of Arthrospira powders from different producers on the formation of endothelial cell monolayers Author(s) Krüger-Genge, Anne, Jung, Conrad H. G., Braune, Steffen, Harb, K., Westphal, S., Klöpzig, Stefanie, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2021 Arthrospira platensis; spirulina; endothelial cells Source Clinical Hemorheology and Microcirculation, S. 193 - 203 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch219200 DOI https://doi.org/10.3233/CH-219200
Inhibition of phase-1 biotransformation and cytostatic effects of diphenyleneiodonium on hepatoblastoma cell line HepG2 and a CYP3A4-overexpressing HepG2 cell clone Author(s) Schulz, Christian, Jung, Friedrich, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2021 Phase-1; biotransformation; CYP; cytochrome P450 monooxygenase; CYP3A4; diphenyleneiodonium; DPI; HepG2; HepG2-CYP3A4; hepatocytes; NADPH-cytochrome P450 oxidoreductase; POR; CPR Source Clinical Hemorheology and Microcirculation, S. 231 - 243 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch219117 DOI https://doi.org/10.3233/CH-219117
Differences in human and sheep platelet adherence, aggregation and activation induced by glass beads in a modified chandler loop-system Author(s) Greif, G., Mrowietz, Christof, Meyer-Sievers, H., Ganter, M., Jung, Friedrich, Hiebl, Bernhard Type Scientific Article ref. Year of publication 2021 Sheep; platelet; activation; platelet volume; CD42a; CD61; CD62P; CD63 Source Clinical Hemorheology and Microcirculation, S. 129 - 136 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch219104 DOI https://doi.org/10.3233/CH-219104
40th conference of the German society for clinical microcirculation and hemorheology (DGKMH) Author(s) Küpper, Jan-Heiner, Krüger-Genge, Anne, Jung, Friedrich Type Scientific Article ref. Year of publication 2021 Source Clinical Hemorheology and Microcirculation, S. 1 - 2 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/ch-219100
Morphology and Growth of Arthrospira platensis during Cultivation in a Flat-Type Bioreactor Author(s) Jung, Conrad H. G., Braune, Steffen, Waldeck, Peter, Küpper, Jan-Heiner, Petrick, Ingolf, Jung, Friedrich Type Scientific Article ref. Year of publication 2021 Arthrospira platensis; Spirulina; life cycle; morphology; fragmentation; fission Source Life Volume 11 Issue/Journal number 6 ISSN 2075-1729 URL https://www.mdpi.com/2075-1729/11/6/536/htm DOI https://doi.org/10.3390/life11060536
Wireless point-of-care ultrasound: First experiences with a new generation handheld device Author(s) Jung, Ernst Michael, Dinkel, J., Verloh, Niklas, Brandenstein, M., Stroszczynski, Christian, Jung, Friedrich, Rennert, J. Type Scientific Article ref. Year of publication 2021 Point-of-care ultrasound; Vscan Air; high-end ultrasound Source Clinical Hemorheology and Microcirculation, S. 463 - 474 Volume 79 Issue/Journal number 3 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch211197 DOI https://doi.org/10.3233/CH-211197
High-performance sonographical multimodal imaging of non cystic thyroid lesions: Chances of the preoperative diagnostics in relation to histopathology Author(s) Brandenstein, M., Wiesinger, Isabel, Jung, Friedrich, Stroszczynski, Christian, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2021 Solid thyroid lesions; high-resolution ultrasound; HR-flow; elastography; CEUS; histopathology Source Clinical Hemorheology and Microcirculation, S. 27 - 38 Volume 79 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch219101 DOI https://doi.org/10.3233/CH-219101
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation Author(s) Künzel, Stephan R., Hoffmann, Maximilian, Weber, Silvio, Künzel, Karolina, Kämmerer, Susanne, Günscht, Mario, Klapproth, Erik, Rausch, Johanna S. E., Sadek, Mirna S., Kolanowski, Tomasz, Meyer-Roxlau, Stefanie, Piorkowski, Christopher, Tugtekin, Sems M., Rose-John, Stefan, Yin, Xiaoke, Mayr, Manuel, Kuhlmann, Jan Dominik, Wimberger, Pauline, Grützmann, Konrad, Herzog, Natalie, Küpper, Jan-Heiner, O’Reilly, Molly, Kabir, S. Nashitha, Sommerfeld, Laura C., Guan, Kaomei, Wielockx, Ben, Fabritz, Larissa, Nattel, Stanley, Ravens, Ursula, Dobrev, Dobromir, Wagner, Michael, El-Armouche, Ali Type Scientific Article ref. Year of publication 2021 atrial fibrillation; fibroblasts; fibrosis; mesalamine; osteopontin Source Circulation Research, S. 804 - 820 Volume 129 Issue/Journal number 8 ISSN 1524-4571 0009-7330 URL https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.121.319425 DOI https://doi.org/10.1161/CIRCRESAHA.121.319425
Arthrospira for use in the treatment of diseases Author(s) Küpper, Jan-Heiner, Jung, Friedrich Type patent Year of publication 2021 Patent number PCT/EP2021/073430 URL https://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwik1t7QrOL5AhVTO-wKHT97CKAQFnoECAQQAQ&url=https%3A%2F%2Fdata.epo.org%2Fpublication-server%2Frest%2Fv1.0%2Fpublication-dates%2F20220302%2Fpatents%2FEP3960193NWA1%2Fdocument.pdf&usg=AOvVaw20GVY_ywjb2xbS0TwSDArJ
In vitro Arzneimittel aus Prodrugs und deren Verwendung Author(s) Scheibner, Katrin, Küpper, Jan-Heiner, Jung, Friedrich Type patent Year of publication 2021 Patent number DE 800845612 URL https://www.b-tu.de/enzymtechnologie/publikationen/patente
Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo Author(s) Vagiannis, Dimitrios, Budagaga, Youssif, Morell, Anselm, Zhang, Yu, Novotna, Eva, Skarka, Adam, Kammerer, Sarah, Küpper, Jan-Heiner, Hanke, Ivo, Rozkoš, Tomáš, Hofman, Jakub Type Scientific Article ref. Year of publication 2021 Source International Journal of Molecular Sciences Volume 22 Issue/Journal number 21 ISSN 1422-0067 1661-6596 DOI https://doi.org/10.3390/ijms222111936
Structure‐dependent genotoxicity and cytotoxicity of eleven pyrrolizidine alkaloids in human liver cells with CYP3A4 overexpression Author(s) Haas, M., Wirachowski, K., Küpper, Jan-Heiner, Schrenk, Dieter, Fahrer, J. Type image Year of publication 2021 DOI https://doi.org/10.1002/lemi.202158135
HepG2-1A2 C2 and C7: Lentivirus vector-mediated stable and functional overexpression of cytochrome P450 1A2 in human hepatoblastoma cells Author(s) Steinbrecht, Susanne, Pfeifer, Nadine, Herzog, Natalie, Katzenberger, Nadine, Schulz, Christian, Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2020 HepG2; CYP1A2; Cytochrome P450; Liver metabolism Source Toxicology Letters, S. 155 - 159 Volume 319 ISSN 0378-4274 DOI https://doi.org/10.1016/j.toxlet.2019.11.006
Effects of acrolein in comparison to its prodrug cyclophosphamide on human primary endothelial cells in vitro Author(s) Lau, S., Rangarajan, R., Krüger-Genge, Anne, Braune, Steffen, Kammerer, Sarah, Küpper, Jan-Heiner, Lendlein, Andreas, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Human umbilical venous endothelial cells; Acrolein; Aneuploidy; von Willebrand factor; in vitro study Source Toxicology in Vitro Volume 62 ISSN 0887-2333 DOI https://doi.org/10.1016/j.tiv.2019.104685
Substrate-enzyme affinity-based surface modification strategy for endothelial cell-specific binding under shear stress Author(s) Lee, Seahyoung, Ganesan, Ramakrishnan, Krüger-Genge, Anne, Kratz, Karl, Franke, Ralf-Peter, Lendlein, Andreas, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 endothelin converting enzyme-1; big endothelin-1; endothelialization; shear resistance Source Clinical Hemorheology and Microcirculation, S. 85 - 98 Volume 75 Issue/Journal number 1 ISSN 1875-8622 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch190736 DOI https://doi.org/10.3233/CH-190736
COVID-19 Author(s) Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Source Clinical Hemorheology and Microcirculation, S. 347 - 348 Volume 74 Issue/Journal number 4 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-209001
Contrast enhanced ultrasonography (CEUS) to detect abdominal microcirculatory disorders in severe cases of COVID-19 infection: First experience Author(s) Jung, Ernst Michael, Stroszczynski, Christian, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Corona virus; contrast enhanced ultrasound sonography (CEUS); COVID-19; liver; kidney Source Clinical Hemorheology and Microcirculation, S. 353 - 361 Volume 74 Issue/Journal number 4 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209003 DOI https://doi.org/10.3233/CH-209003
Contrast enhanced ultrasound (CEUS) to assess pleural pulmonal changes in severe Covid 19 infection: First results Author(s) Jung, Ernst Michael, Stroszczynski, Christian, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 COVID-19 infection; lung- Contrast-enhanced ultrasound (CEUS); pleural affection; peripheral embolic consolidation Source Clinical Hemorheology and Microcirculation, S. 19 - 26 Volume 75 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209005 DOI https://doi.org/10.3233/CH-209005
A.L. Copley Best Paper Prize 2019 Author(s) Jung, Friedrich, Connes, Philippe, Lehmann, Christian Type Scientific Article ref. Year of publication 2020 Source Clinical Hemorheology and Microcirculation, S. 1 - 2 Volume 75 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://europepmc.org/article/med/32568189 DOI https://doi.org/10.3233/ch-209100
Histological and SEM assessment of blood stasis in kidney blood vessels after repeated intra-arterial application of radiographic contrast media Author(s) Lamby, Philipp, Minkow, Alexander, Handt, Stefan, Falter, Johannes, Schellenberg, Eva-Lotte, Graf, Stefanie, Hiebl, Bernhard, Haerteis, Silke, Gemeinhardt, Ole, Krüger-Genge, Anne, Klosterhalfen, Bernd, Jung, Ernst Michael, Franke, Ralf-Peter, Momeni, Arash, Prantl, Lukas, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 acute kidney injury; nephrotoxicity; nephropathy; renal pathology; iodinated contrast media; electron microscopy; histopathology Source Life Volume 10 Issue/Journal number 9 ISSN 2075-1729 URL https://www.mdpi.com/2075-1729/10/9/167 DOI https://doi.org/10.3390/life10090167
Effects of gut microbial metabolite trimethylamine N-oxide (TMAO) on platelets and endothelial cells Author(s) Krüger-Genge, Anne, Jung, Friedrich, Hufert, Frank, Jung, Ernst Michael, Küpper, Jan-Heiner, Storsberg, J. Type Scientific Article ref. Year of publication 2020 Microbiome; trimethylamin-N-oxide; platelets; endothelial cells; atherosclerosis Source Clinical Hemorheology and Microcirculation, S. 309 - 316 Volume 76 Issue/Journal number 2 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209206 DOI https://doi.org/10.3233/CH-209206
Cutaneous microcirculation in patients with peripheral arterial occlusive disease: Comparison of capillary blood circulation in the nail fold of finger and toe Author(s) Mrowietz, Christof, Sievers, H., Pindur, Gerhard, Hiebl, Bernhard, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Microcirculation; peripheral arterial occlusive disease; capillary microscopy Source Clinical Hemorheology and Microcirculation, S. 279 - 285 Volume 76 Issue/Journal number 2 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209220 DOI https://doi.org/10.3233/CH-209220
Imaging of breast implant and implant-associated complications: Capsular contracture and intraor extracapsular rupture Author(s) Martina, Georgieva, Kammerer, Sarah, Prantl, Lukas, Jung, Friedrich, Stroszczynski, Christian, Jung, Ernst Michael Type Scientific Article ref. Year of publication 2020 Breast implant; ultrasound; magnetic resonance imaging; capsular contracture Source Clinical Hemorheology and Microcirculation, S. 221 - 231 Volume 76 Issue/Journal number 2 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209218 DOI https://doi.org/10.3233/CH-209218
Contrast enhanced ultrasound (CEUS) with parametric imaging and time intensity curve analysis (TIC) for evaluation of the success of prostate arterial embolization (PAE) in cases of prostate hyperplasia Author(s) Jung, Ernst Michael, Wertheimer, T., Putz, F. J., Jung, Friedrich, Kammerer, Sarah, Pregler, B., Luerken, L., Stroszczynski, Christian, Beyer, L. Type Scientific Article ref. Year of publication 2020 Contrast enhanced ultrasound (CEUS); parametric imaging; time intensity curve analysis (TIC); prostate arterial embolization (PAE) Source Clinical Hemorheology and Microcirculation, S. 143 - 153 Volume 76 Issue/Journal number 2 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209202 DOI https://doi.org/10.3233/CH-209202
Interaction between extracellular cancer matrix and stromal breast cells Author(s) Gehmert, Sangaa, Lehoczky, Gyözöc, Loibl, Markus, Jung, Friedrich, Prantl, Lukas, Gehmert, Sebastian Type Scientific Article ref. Year of publication 2020 Breast cancer; extracellular matrix; microenvironment; epithelial-stromal interaction Source Clinical Hemorheology and Microcirculation, S. 45 - 52 Volume 74 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch199234 DOI https://doi.org/10.3233/CH-199234
Aptamer supported in vitro endothelialization of poly(ether imide) films Author(s) Schulz, Christian, Krüger-Genge, Anne, Jung, Friedrich, Lendlein, Andreas Type Scientific Article ref. Year of publication 2020 aptamer; endothelialization; physical functionalization; poly(ether imide) films; shear resistance Source Clinical Hemorheology and Microcirculation, S. 201 - 217 Volume 75 Issue/Journal number 2 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-190775
Ultrasound elastography for the detection of capsular fibrosis in breast implants: First results Author(s) Jung, Ernst Michael, Hösl, Vanessa, Fraunberg, Sarah von, Jung, Friedrich, Prantl, Lukas Type Scientific Article ref. Year of publication 2020 Capsular fibrosis; ultrasound examinations; elastography; ARFI; Baker score Source Clinical Hemorheology and Microcirculation, S. 247 - 257 Volume 77(2021) Issue/Journal number 3 ISSN 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch200875 DOI https://doi.org/10.3233/CH-200875
39th conference of the German society for clinical microcirculation and hemorheology (DGKMH) Author(s) Hiebl, Bernhard, Krüger-Genge, Anne, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Source Clinical Hemorheology and Microcirculation, S. 121 - 122 Volume 76 Issue/Journal number 2 ISSN 1875-8622 1386-0291 URL https://europepmc.org/article/med/33074223 DOI https://doi.org/10.3233/ch-209200
Real time monitoring of oxygen uptake of hepatocytes in a microreactor using optical microsensors Author(s) Gehre, Christian P., Flechner, Marie, Kammerer, Sarah, Küpper, Jan-Heiner, Coleman, Charles Dominic, Püschel, Gerhard Paul, Uhlig, Katja, Duschl, Claus Type Scientific Article ref. Year of publication 2020 Biophysics; Biotechnology; Cell biology; Drug discovery Source Scientific Reports Volume 10 ISSN 2045-2322 URL https://www.nature.com/articles/s41598-020-70785-6 DOI https://doi.org/10.1038/s41598-020-70785-6
Estragole: DNA adduct formation in primary rat hepatocytes and genotoxic potential in HepG2-CYP1A2 cells Author(s) Schulte-Hubbert, Ruth, Küpper, Jan-Heiner, Thomas, Adam D., Schrenk, Dieter Type Scientific Article ref. Year of publication 2020 Estragole; Carcinogenicity; DNA adducts; Genotoxicity; Hepatoma; Liver cells Source Toxicology Volume 444 ISSN 0300-483X URL https://www.sciencedirect.com/science/article/pii/S0300483X20302055 DOI https://doi.org/10.1016/j.tox.2020.152566
Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells Author(s) Rutz, Lukas, Gao, Lan, Küpper, Jan-Heiner, Schrenk, Dieter Type Scientific Article ref. Year of publication 2020 Genotoxicity; Liver cells; Micronuclei; Mutagenicity; Pyrrolizidine alkaloids; Relative potencies Source Archives of Toxicology, S. 4159 - 4172 Volume 94 Issue/Journal number 12 ISSN 0340-5761 1432-0738 URL https://link.springer.com/article/10.1007/s00204-020-02895-z DOI https://doi.org/10.1007/s00204-020-02895-z
Modeling atrial fibrosis in vitro - Generation and characterization of a novel human atrial fibroblast cell line Author(s) Künzel, Stephan R., Rausch, Johanna S. E., Schäffer, Charlotte, Hoffmann, Maximilian, Künzel, Karolina, Klapproth, Erik, Kant, Theresa, Herzog, Natalie, Küpper, Jan-Heiner, Lorenz, Kristina, Dudek, Svenja, Emig, Ramona, Ravens, Ursula, Rog‐Zielinska, Eva A., Peyronnet, Rémi, El-Armouche, Ali Type Scientific Article ref. Year of publication 2020 cardiovascular disease; cell culture; cell lines; fibroblasts; fibrosis; heart Source FEBS Open Bio, S. 1210 - 1218 Volume 10 Issue/Journal number 7 ISSN 2211-5463 DOI https://doi.org/10.1002/2211-5463.12896
How we should respond to the Coronavirus SARS-CoV-2 outbreak: A German perspective Author(s) Jung, Friedrich, Krieger, Volker, Hufert, Frank, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2020 Corona virus; SARS-CoV-2; COVID-19; herd immunity; hammer and dance strategy Source Clinical Hemorheology and Microcirculation, S. 363 - 372 Volume 74 Issue/Journal number 4 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209004 DOI https://doi.org/10.3233/CH-209004
A comparison of mortality rates between European and Asian States Author(s) Küpper, Jan-Heiner, Jung, Friedrich, Krieger, Volker, Hufert, Frank Type Scientific Article ref. Year of publication 2020 Source Clinical Hemorheology and Microcirculation, S. 3 - 5 Volume 75 Issue/Journal number 1 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-209008
COVID-19 and the endothelium Author(s) Jung, Friedrich, Krüger-Genge, Anne, Franke, Ralf-Peter, Hufert, Frank, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2020 COVID-19; endocytosis; endothelial cell dysfunction; endotheliitis Source Clinical Hemorheology and Microcirculation, S. 7 - 11 Volume 75 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209007 DOI https://doi.org/10.3233/CH-209007
Herd immunity or suppression strategy to combat COVID-19 Author(s) Jung, Friedrich, Krieger, Volker, Hufert, Frank, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2020 COVID-19; strategy; Sweden; Taiwan; Germany Source Clinical Hemorheology and Microcirculation, S. 13 - 17 Volume 75 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209006 DOI https://doi.org/10.3233/CH-209006
Synthesis of cyclophosphamide metabolites by a peroxygenase from Marasmius rotula for toxicological studies on human cancer cells Author(s) Steinbrecht, Susanne, Kiebist, Jan, König, Rosalie, Thiessen, Markus, Schmidtke, Kai-Uwe, Kammerer, Sarah, Küpper, Jan-Heiner, Scheibner, Katrin Type Scientific Article ref. Year of publication 2020 Biocatalysis; Cyclophosphamide; Human drug metabolites; Peroxygenase; Toxicity Source AMB Express Volume 10 ISSN 2191-0855 URL https://amb-express.springeropen.com/articles/10.1186/s13568-020-01064-w DOI https://doi.org/10.1186/s13568-020-01064-w
Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme Author(s) Vagiannis, Dimitrios, Novotna, Eva, Skarka, Adam, Kammerer, Sarah, Küpper, Jan-Heiner, Chen, Si, Guo, Lei, Staud, Frantisek, Hofman, Jakub Type Scientific Article ref. Year of publication 2020 ensartinib; cancer; multidrug resistance; drug-drug interaction; ABC transporter; cytochrome P450 Source Cancers Volume 12 Issue/Journal number 4 ISSN 2072-6694 URL https://www.mdpi.com/2072-6694/12/4/813 DOI https://doi.org/10.3390/cancers12040813
Age-related morphology and function of human arterial endothelial cells Author(s) Lau, S., Rangarajan, R., Krüger-Genge, Anne, Braune, Steffen, Küpper, Jan-Heiner, Lendlein, Andreas, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Cardiovascular implants; arterial endothelial cells; aging; senescence; donor variability Source Clinical Hemorheology and Microcirculation, S. 93 - 107 Volume 74 Issue/Journal number 1 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch199238 DOI https://doi.org/10.3233/CH-199238
Namibian algae species: A review of their distribution, medicinal uses and chemical constituents Author(s) Rahman, Ateeq, Moola, Nyambe, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2020 Source Journal of Cellular Biotechnology, S. 139 - 159 Volume 6 Issue/Journal number 2 URL https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb209010 DOI https://doi.org/10.3233/JCB-209010
Effect of Prostanoids on Human Platelet Function: An Overview Author(s) Braune, Steffen, Küpper, Jan-Heiner, Jung, Friedrich Type Scientific Article ref. Year of publication 2020 Source International Journal of Molecular Science Volume 21 Issue/Journal number 23 URL https://www.mdpi.com/1422-0067/21/23/9020 DOI https://doi.org/10.3390/ijms21239020
Verfahren zur Herstellung von biogenen Stoffen Author(s) Scheibner, Katrin, Küpper, Jan-Heiner, Schmidtke, Kai-Uwe, Miethbauer, Sebastian, Herzog, Natalie Type patent Year of publication 2020 Patent number EP 3068868 B1 URL https://patents.google.com/patent/EP3068868B1/de
Verfahren zur enzymatischen Herstellung von zytostatischen 4-Hydroxy-Oxazaphosphorinen“ Author(s) Scheibner, Katrin, Kiebist, Jan, Schmidtke, Kai-Uwe, Küpper, Jan-Heiner Type patent Year of publication 2020 Patent number DE 10 2020 202 357.3 URL https://www.b-tu.de/enzymtechnologie/publikationen/patente
Growth-related micromorphological characteristics of the porcine femoral artery Author(s) Nies, A., Proft, L., Nehring, M. E., Gruber, Cnristian, Sievers, H., Hünigen, Hana, Rodruigues, A. G., Gemeinhardt, Ole, Mrowietz, Christof, Jung, Friedrich, Hiebl, Bernhard Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation, S. 195 - 201 Volume 73 Issue/Journal number 1 ISSN 1875-8622 DOI https://doi.org/10.3233/CH-199219
Imaging of coronary arteries using ionic versus non-ionic radiographic contrast media: Intraindividual comparison study Author(s) Gerk, U., Franke, Ralf-Peter, Jung, Ernst Michael, Scheller, B., Krüger-Genge, Anne, Jung, Friedrich Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation ISSN 1875-8622 DOI https://doi.org/10.3233/CH-199217
HELP-(Heparin-induced Extracorporeal LDL Precipitation)-apheresis in heart recipients with cardiac allograft vasculopathy and concomitant hypercholesterolemia: Influence of long-term treatment on the microcirculation Author(s) Park, J. W., Matschke, K., Mrowietz, Christof, Krüger-Genge, Anne, Jung, Friedrich Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation, S. 19 - 27 Volume 73 Issue/Journal number 1 ISSN 1875-8622 DOI https://doi.org/10.3233/CH-199216
Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance Author(s) Hofman, Jakub, Sorf, Ales, Vagiannis, Dimitrios, Sucha, Simona, Novotna, Eva, Kammerer, Sarah, Küpper, Jan-Heiner, Ceckova, Martina, Staud, Frantisek Type Scientific Article ref. Year of publication 2019 Source Drug Metabolism and Disposition, S. 699 - 709 Volume 47 Issue/Journal number 7 ISSN 1521-009X 0090-9556 DOI https://doi.org/10.1124/dmd.119.086975
HepG2 cells with recombinant cytochrome P450 enzyme overexpression: Their use and limitation as in vitro liver model Author(s) Steinbrecht, Susanne, Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2019 Source Journal of Cellular Biotechnology, S. 55 - 64 Volume 5 Issue/Journal number 1 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-189013
Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes Author(s) Hofman, Jakub, Sorf, Ales, Vagiannis, Dimitrios, Sucha, Simona, Kammerer, Sarah, Küpper, Jan-Heiner, Chen, Si, Guo, Lei, Ceckova, Martina, Staud, Frantisek Type Scientific Article ref. Year of publication 2019 Source Molecular Pharmaceutics, S. 4436 - 4450 Volume 16 Issue/Journal number 11 DOI https://doi.org/10.1021/acs.molpharmaceut.9b00361
Colon cancer cells cultured under hyperosmotic conditions as in vitro model to investigate dehydration effects on cancer drug susceptibility Author(s) Haileka, Vanessa, George, Sandra, Steinbrecht, Susanne, Jung, Friedrich, Reinehr, R., Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation, S. 169 - 176 Volume 73 Issue/Journal number 1 ISSN 1875-8622 DOI https://doi.org/10.3233/CH-199210
NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies Author(s) Schulz, Christian, Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation, S. 249 - 260 Volume 73 Issue/Journal number 1 ISSN 1386-0291 DOI https://doi.org/10.3233/CH-199226
Vascular Endothelial Cell Biology: An Update Author(s) Krüger-Genge, Anne, Blocki, Anna, Franke, Ralf-Peter, Jung, Friedrich Type Scientific Article ref. Year of publication 2019 Source International Journal of Molecular Sciences Volume 20 Issue/Journal number 18 ISSN 1422-0067 1661-6596 DOI https://doi.org/10.3390/ijms20184411
A.L. Copley Best Paper Prize 2018 Author(s) Jung, Friedrich, Connes, Philippe, Lehmann, Christian Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation, S. 117 - 118 Volume 72 Issue/Journal number 2 ISSN 1386-0291 DOI https://doi.org/10.3233/CH-199008
Spirulina platensis, a super food? Author(s) Jung, Friedrich, Krüger-Genge, Anne, Waldeck, Peter, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2019 Spirulina; health effects; dietary supplements; liver protection; virus infection; HIV; nutrition; animal feeding Source Journal of Cellular Biotechnology, S. 43 - 54 Volume 5 Issue/Journal number 1 ISSN 2352-3689 2352-3697 URL https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb189012 DOI https://doi.org/10.3233/JCB-189012
Factors influencing the growth of Spirulina platensis in closed photobioreactors under CO₂ – O₂ conversion Author(s) Jung, Friedrich, Jung, Conrad H. G., Krüger-Genge, Anne, Waldeck, Peter, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2019 spirulina platensis; influencing factors; temperature; light intensity; wave length Source Journal of Cellular Biotechnology, S. 125 - 134 Volume 5 Issue/Journal number 2 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-199004
Regulation of bone regeneration Author(s) Jung, Friedrich, Pietzsch, Jens Type Scientific Article ref. Year of publication 2019 Source Clinical Hemorheology and Microcirculation, S. 379 - 380 Volume 73 Issue/Journal number 3 ISSN 1875-8622 1386-0291 URL https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch199101 DOI https://doi.org/10.3233/CH-199101
Editorial Author(s) Wiggermann, P., Krüger-Genge, Anne, Jung, Friedrich Type Conference Proceeding no refering Year of publication 2019 Publisher name IOS Press Source Selected papers of the 38th Conference of the German Society for Clinical Microcirculation and Hemorheology, 21-23 November 2019, Braunschweig, Germany URL https://pubmed.ncbi.nlm.nih.gov/31561330/#affiliation-3 DOI https://doi.org/10.3233/CH-199200
Evidence for cytostatic effect of cyclophosphamide on human vein endothelial cells in cancer therapy: preliminary in vitro results. Author(s) Krüger-Genge, Anne, Steinbrecht, Susanne, Küpper, Jan-Heiner, Lendlein, Andreas, Jung, Friedrich Type Scientific Article ref. Year of publication 2018 Source Clinical Hemorheology and Microcirculation, S. 267 - 276 Volume 69 Issue/Journal number 1-2 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-189125
Human Hepatocyte Systems for in vitro Toxicology Analysis. Author(s) Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2018 Source Journal of Cellular Biotechnology, S. 85 - 93 Volume 3 Issue/Journal number 2 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-179012
Optimized protocol for induction of cytochrome P450 enzymes 1A2 and 3A4 in human primary-like hepatocyte cell strain HepaFH3 to study in vitro toxicology Author(s) Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2018 Source Clinical Hemorheology and Microcirculation, S. 563 - 571 Volume 70 Issue/Journal number 4 ISSN 1386-0291 1875-8622 DOI https://doi.org/10.3233/CH-189321
Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4 Author(s) Steinbrecht, Susanne, König, Rosalie, Schmidtke, Kai-Uwe, Herzog, Natalie, Scheibner, Katrin, Krüger-Genge, Anne, Jung, Friedrich, Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2018 Source Toxicology, S. 37 - 47 Volume 412 ISSN 0300-483X DOI https://doi.org/10.1016/j.tox.2018.11.008
Influence of surface treatments of poly(n-butyl acrylate) networks on fibroblasts adhesion, morphology and viability Author(s) Krüger-Genge, Anne, Braune, Steffen, Walter, Maria, Kratz, Karl, Küpper, Jan-Heiner, Krengel, M., Lendlein, Andreas, Jung, Friedrich Type Scientific Article ref. Year of publication 2018 Source Clinical Hemorheology and Microcirculation, S. 305 - 316 Volume 69 Issue/Journal number 1-2 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-189130
ATP-based cell viability assay is superior to trypan blue exclusion and XTT assay in measuring cytotoxicity of anticancer drugs Taxol and Imatinib, and proteasome inhibitor MG-132 on human hepatoma cell line HepG2. Author(s) Nowak, Elisabeth, Kammerer, Sarah, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2018 Source Clinical Hemorheology and Microcirculation, S. 327 - 336 Volume 69 Issue/Journal number 1-2 ISSN 1386-0291 1875-8622 DOI https://doi.org/10.3233/CH-189120
Real-time monitoring of oxygen consumption of hepatocytes in a microbioreactor Author(s) Uhlig, Katja, Gehre, Christian P., Kammerer, Sarah, Küpper, Jan-Heiner, Coleman, D., Püschel, G., Duschl, Claus Type Conference Proceeding refering Year of publication 2018 Source Toxicology Letters, S. 115 DOI https://doi.org/10.1016/j.toxlet.2018.06.652
Actin type and distribution in erythrocytes Author(s) Krüger-Genge, Anne, Jung, Friedrich, Küpper, Jan-Heiner, Lehmann, Christian, Franke, Ralf-Peter Type Scientific Article ref. Year of publication 2018 Erythrocytes; echinocytes; submembraneous cytoskeleton; actin Source Journal of Cellular Biotechnology, S. 81 - 83 Volume 3 Issue/Journal number 2 ISSN 2352-3697 2352-3689 URL https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb179014 DOI https://doi.org/10.3233/JCB-179014
Bacterial production and purification of immunoreactive paraneoplastic neurological syndrome autoantigen Ma2 Author(s) Nowak, Elisabeth, Martin, F., George, Sandra, Röber, Nadja, Conrad, Karsten, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2017 Autoimmune disease; autoantibodies; dot blot immunoassay; FPLC; IMAC; Ma2; PNMA2; PNS; T7 expression system Source Journal of Cellular Biotechnology, S. 85 - 91 Volume 2 Issue/Journal number 2 ISSN 2352-3697 URL https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb15029 DOI https://doi.org/10.3233/JCB-15029
Vorrichtung und Verfahren zur Sequestrierung von atmosphärischen Kohlendioxid Author(s) Küpper, Jan-Heiner Type patent Year of publication 2017 Patent number EP 17 200 037.4
Entwicklung zellbasierter Assays zur Routine-Diagnostik von Autoimmunerkrankungen am Beispiel von Myasthenia gravis Author(s) George, Sandra Type doctoralthesis Year of publication 2017
Chronic ethanol treatment depletes glutathione regeneration capacity in hepatoma cell line HepG2 Author(s) Kade, S., Herzog, Natalie, Schmidtke, Kai-Uwe, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2016 Source Journal of Cellular Biotechnology, S. 183 - 190 Volume 1 Issue/Journal number 2 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-15019
Primary like human hepatocytes genetically engineered to obtain proliferation competence display liver biotransformation activity in 2D and 3D culture systems Author(s) Herzog, Natalie, Hansen, Max, Miethbauer, Sebastian, Schmidtke, Kai-Uwe, Anderer, Ursula, Lupp, Amelie, Sperling, Sebastian, Seehofer, Daniel, Damm, Georg, Scheibner, Katrin, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2016 Source Cell Biology International, S. 341 - 353 Volume 40 Issue/Journal number 3 ISSN 1095-8355 1065-6995
Development of multiplex PCR systems for expression profiling of human cardiomyocytes induced to profilerate by lentivirus transduction of upcyte genes Author(s) George, Sandra, Rödiger, Stefan, Schröder, Christian, Knaut, Michael, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2016 Source Journal of Cellular Biotechnology, S. 35 - 55 Volume 2 Issue/Journal number 1 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-15025
Adenoviral vectors for modulation of poly(ADP-ribose) polymerase-1 (PARP1) - dependent DNA repair as a predictive tool for chemotherapy Author(s) Meyer, Ralph G., Meyer-Ficca, Mirella, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2016 Source Journal of Cellular Biotechnology, S. 57 - 68 Volume 2 Issue/Journal number 1 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-15026
Critical evaluation of KCNJ3 gene product detection in human breast cancer: MRNA in situ hybridisation is superior to immunohistochemistry Author(s) Kammerer, Sarah, Jahn, Stephan Wenzel, Winter, Elke, Eidenhammer, Sylvia, Rezania, Simin, Regitnig, Peter, Pichler, Martin, Schreibmayer, Wolfgang, Bauernhofer, Thomas Type Scientific Article ref. Year of publication 2016 Source Journal of Clinical Pathology, S. 1116 - 1121 Volume 69 Issue/Journal number 12 ISSN 1472-4146 0021-9746 DOI https://doi.org/10.1136/jclinpath-2016-203798
Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner Author(s) Rezania, Simin, Kammerer, Sarah, Li, Chouyang, Steinecker-Frohnwieser, Bibiane, Gorischek, Astrid, Devaney, Trevor Thomas Joseph, Verheyen, Sarah, Passegger, Christina, Ghaffari Tabrizi-Wizsy, Nassim, Hackl, Hubert, Platzer, Dieter, Zarnani, A.H., Malle, Ernst, Jahn, Stephan Wenzel, Bauernhofer, Thomas, Schreibmayer, Wolfgang Type Scientific Article ref. Year of publication 2016 Source BMC Cancer Volume 16 ISSN 1471-2407 DOI https://doi.org/10.1186/s12885-016-2664-8
KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients Author(s) Kammerer, Sarah, Sokolowski, Armin Andreas, Hackl, Hubert, Platzer, Dieter, Jahn, Stephan Wenzel, El-Heliebi, Amin, Schwarzenbacher, Daniela, Stiegelbauer, Verena, Pichler, Martin, Rezania, Simin, Fiegl, Heidelinde, Peintinger, Florentia, Regitnig, Peter, Höfler, Gerald, Schreibmayer, Wolfgang, Bauernhofer, Thomas Type Scientific Article ref. Year of publication 2016 Source OncoTarget : open access impact journal, S. 84705 - 84717 Volume 7 Issue/Journal number 51 DOI https://doi.org/10.18632/oncotarget.13224
Generation of cytochrome P450 3A4-overexpressing HepG2 cell clones for standardization of hepatocellular testosterone 6β-hydroxylation activity Author(s) Herzog, Natalie, Katzenberger, Nadine, Martin, Frank, Schmidtke, Kai-Uwe, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2015 Source Journal of Cellular Biotechnology, S. 15 - 26 Volume 1 Issue/Journal number 1 ISSN 2352-3697 2352-3689 DOI https://doi.org/10.3233/JCB-15002
Expression of nicotinic acetylcholine receptor subunits in HEp-2 cells for immunodetection of autoantibody specificities in sera fro Myasthenia gravis patients Author(s) George, Sandra, Noack, M., Vanek, Monika, Rentzsch, J., Röber, Nadja, Roggenbuck, Dirk, Conrad, Karsten, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2015 Source Clinical Hemorheology and Microcirculation, S. 385 - 396 Volume 61 Issue/Journal number 2 ISSN 1875-8622 1386-0291 DOI https://doi.org/10.3233/CH-151999
It’s the planet, stupid! Sieben Perspektiven zum Klimawandel : mit Interviewbeiträgen von Hartmut Graßl, Hans-Werner Sinn, Ernst-Ulrich von Weizsäcker, Meinhard Miegel, Mathias Binswanger, Enoch zu Guttenberg und Wulf Schiefenhövel Author(s) Paumen, Anja, Küpper, Jan-Heiner Type book Year of publication 2015 Publisher name München : oekom Verlag ISBN 978-3-86581-739-6 3-86581-739-4
Expression of nicotinic acetylcholine receptor subunits in HEp-2 cells for immunodetection of autoantibody specificities in sera from Myasthenia gravis patients Author(s) George, Sandra, Noack, Monika, Vanek, Monika, Rentzsch, Juliane, Röber, Nadja, Conrad, Karsten, Roggenbuck, Dirk, Küpper, Jan-Heiner Type conference publication Year of publication 2015 Publisher name Lengerich : Pabst Science Publishers Source From autoantibody research to standardized diagnostic assays in the management of human diseases, report on the 12th Dresden Symposium on Autoantibodies, September 23-26, 2015, S. 195 - 196 ISBN 978-3-95853-104-8 Autoantigens, autoantibodies, autoimmunity ; Volume 10
Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: Down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Author(s) Verbrugge, Sue Ellen, Al, Marjon, Assaraf, Yehuda G., Kammerer, Sarah, Chandrupatla, Durga, Honeywell, Richard, Musters, Rene, Giovannetti, Elisa, O`Toole, Tom, Scheffer, George L., Krige, David, Gruijl, Tanja de, Niessen, Hans W.M., Lems, Willem F., Kramer, Pieternella A., Scheper, Rik J., Cloos, Jacqueline, Ossenkoppele, Gert, Peters, Godefridus J., Jansen, Gerrit Type Scientific Article ref. Year of publication 2015 Source OncoTarget : open access impact journal, S. 5240 - 5257 Volume 7 Issue/Journal number 5 ISSN 1949-2553 DOI https://doi.org/10.18632/oncotarget.6169
Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line Author(s) Li, Chouyang, Rezania, Simin, Kammerer, Sarah, Sokolowski, Armin Andreas, Devaney, Trevor Thomas Joseph, Gorischek, Astrid, Jahn, Stephan Wenzel, Hackl, Hubert, Groschner, Klaus, Windpassinger, Christian, Malle, Ernst, Bauernhofer, Thomas, Schreibmayer, Wolfgang Type Scientific Article ref. Year of publication 2015 Source Scientific Reports Volume 5 ISSN 2045-2322 DOI https://doi.org/10.1038/srep08364
Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis Author(s) George, Sandra, Paulick, Silvia, Knütter, Ilka, Röber, Nadja, Hiemann, Rico, Roggenbuck, Dirk, Conrad, Karsten, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2014 Source PLOS one, S. 83924 Volume 9 Issue/Journal number 1 ISSN 1932-6203 DOI https://doi.org/10.1371/journal.pone.0083924
A strategy for cell-based multiplex diagnostics of Myasthenia gravis and autoimmune encephalitis by modifying the subcellular localization of cell membrane autoantigensgravis Author(s) George, Sandra, Georgi, M., Roggenbuck, Dirk, Conrad, Karsten, Küpper, Jan-Heiner Type Scientific Article ref. Year of publication 2014 Source Clinical Hemorheology and Microcirculation, S. 211 - 228 Volume 58 Issue/Journal number 1 ISSN 1386-0291 1875-8622 DOI https://doi.org/10.3233/CH-141897
Tumor-associated autoantibodies Author(s) Conrad, Karsten, Küpper, Jan-Heiner Editor(s) Shoenfeld, Yehuda, Meroni, Pier Luigi, Gershwin, M. Eric Type part of book (chapter) Year of publication 2014 Publisher name Amsterdam [u.a.] : Elsevier Source Autoantibodies, S. 275 - 287 ISBN 978-0-444-56378-1 978-0-444-59377-1
Direct detection of Kitasatospora species with a chaperone oligonucleotide microarray method lacking PCR amplification Author(s) Guenther, Sebastian, Groth, Ingrid, Schierack, Peter, Grabley, Susanne, Munder, Thomas Type Scientific Article ref. Year of publication 2008 Source Journal of basic microbiology, S. 315 - 318 Volume 48 Issue/Journal number 4 ISSN 1521-4028 0233-111X DOI https://doi.org/10.1002/jobm.200800038
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