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Chair of Molecular Cell Biology Prof. Dr. rer. nat. habil. Jan-Heiner Küpper

Annual Meeting of the German Society for Clinical Microcirculation and Hemorheology, May 2022, Senftenberg, Germany

Talk: Jung, F. Effekte von Mikroalgen auf Gewebs- und Blutzellen.

Talk: Braune S, Zeitler C, Jung CGH, Kammerer S, Jung F, Küpper J-H. Effekte wässriger Extrakte von Arthrospira platensis auf Tumorzellen.

Talk: Krüger-Genge A, Harb K, Jung CGH, Braune S, Küpper J-H, Storsberg J, Jung F. Vergleichende Untersuchung verschiedener Arthrospira platensis Produkte auf Endothelzellen.

Talk: Dong Yi, Jung F, Jung EM. CEUS Perfusion – Aktuelle Entwicklungen für die multimodale Tumordiagnostik.

Talk: Kammerer S, Küpper J-H. Validierung neuer Zellmodelle zur Untersuchung von Hepatotoxizität.

Talk: Lau S, Gossen M, Lendlein A, Jung F. Differential sensitivity of assays for determining endothelial cell senescence.

Talk: Jung EM, Jung F, Dong Yi. Möglichkeiten moderner Gefäßultraschallverfahren der portal-venösen Gefäße.

Talk: Schulz C, Jung F, Küpper J-H. Phase I inhibition and toxic effects of diphenyleneiodonium on the hepatic in vitro model HepG2.

Speed Lecture: Zeitler C, Waldeck P, C. CGH Jung, S. Braune, F. Jung, J.-H. Küpper, I. Petrick. Growth and pigment development of Arthrospira platensis during nitrogen depletion.

Speed Lecture: Baumgart J, Herzog N, Schulz C, Kammerer S, Nörenberg A, Küpper J-H. Generation of primary-like hepatocyte systems with inducible proliferation.

Speed Lecture: Jung CGH, Waldeck P, Petrick I, Braune S, Küpper J-H, Jung F. Bioreactor for the cultivation of Arthrospira platensis under controlled conditions.

Speed Lecture: Anders L, Küpper J-H, Kammerer S. In vitro Zellmodelle zur Untersuchung altersphysiologischer Veränderungen des Lebermetabolismus.

Speed Lecture: Köhler S, Kammerer S, Herzog N, Sowa M, Roggenbuck D, Küpper J-H. Generierung und Optimierung MuSK überexprimierender HEp-2 Zellen für den serologischen Nachweis von MuSK Autoantikörpern bei Myasthenia gravis.

Speed Lecture: Locke L, Köhler S, Herzog N, Sowa M, Roggenbuck D, Küpper J-H. Validierung CYP2D6 überexprimierender HepG2 Zellen zur Verwendung für die serologische Diagnostik autoimmuner Lebererkrankungen.

15th Dresden Symposium on Autoantibodies, September 2021, Dresden, Deutschland

Poster: Köhler, S., Locke, L., Kammerer, S., Herzog, N., Schulz, C., George, S., Sowa, M., Röber, N., Conrad, K., Roggenbuck, D., Küpper, J.-H. Lentivirus-mediated generation of autoantigen-overexpressing human cell lines for immunofluorescence-based diagnostics of autoimmune diseases.

 

Ten Years Doctoral Program of Medical Science, November 2018, Medical Universiy of Graz, Austria

Alumni presentation: Kammerer, S.From Graz to Senftenberg via Berlin.

6th Eurosummer School on Biorheology & Symposium on Micro- and Nanomechanics and Mechanobiology of Cells, Tissues and Systems, August 2018, Varna, Bulgaria

Vortrag: Steinbrecht, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Kammerer, S., Küpper, J.-H.Metabolic activity testing underestimates acute cytotoxicity of CPA as revealed by CYP overexpressing HepG2 cell clones.

Vortrag: Kammerer, S.,Steinbrecht, S., Küpper, J.-H. Optimized culture conditions of the human proliferative liver cell line HepaFH3 for toxicity studies.

International Biotech Innovation Days (IBID), May 2018, Senftenberg, Germany

Talk: Steinbrecht, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Kammerer, S., Küpper, J.-H.Metabolic activity testing underestimates acute cytotoxicity of cyclophosphamide as revealed by cytochrome P450 overexpressing human hepatoma cell clones.

Annual Meeting of the German Society for Clinical Microcirculation and Hemorheology, June 2018, Neubrandenburg, Germany

Talk: Kammerer, S.,Steinbrecht, S., Küpper, J.-H.Optimierung von Kulturbedingungen der teilungsfähigen humanen Leberzelllinie HepaFH3 für Toxizitätsuntersuchungen.

Talk: Nowak, E., Kammerer, S., Küpper, J.-H.Etablierung eines Kokultur-Systems von Tumor- und Leberzellen für Wirksamkeits- und Toxizitätsuntersuchungen von Krebstherapeutika unter Berücksichtigung des First-Pass-Effekts.

Talk: Steinbrecht, S.,Kammerer, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Küpper, J.-H.Metabolic activity testing underestimates acute cytotoxicity of cyclophosphamide as revealed by cytochrome P450 overexpressing human hepatoma cell clones.

Talk: Haileka, V., George, S., Steinbrecht, S., Küpper, J.-H.Metabolic activity of Colon Carcinoma Cell lines treated with Cyclophosphamide.

 

Annual Meeting of the German Society for Clinical Microcirculation and Hemorheology, June 2017, Greifswald, Germany

Talk: von Auw, N., George, S., Schmidtke, K.-U., Küpper, J.-H.Flow cytometry analyses for optimization of co-transfection efficiencies of plasmid constructs into mammalian cell lines.

Annual Meeting of the German Society for Clinical Microcirculation and Hemorheology, November 2016, Main, Germany

Talk: Steinbrecht, S., Herzog, N., Schmidtke, K.-U., Scheibner, K., Küpper, J.-H.Human CYP450 2C19 overexpressing HepG2 cell clone for drug testing.

Poster: Herzog, N., Katzenberger, N., Steinbrecht, S., Schmidtke, K.-U., Scheibner, K., Küpper, J.-H.Adaptation of human CYP450 3A4 overexpressing hepatoma cell line HepG2 to endothelial cell culture medium.

Poster: George, S., Rödiger, S., Schröder, C., Knaut, M., Küpper, J.-H.Development of multiplex PCR systems for expression profiling of human cardiomyocytes induced to proliferate by lentivirus transduction of upcyte genes.

Poster: Nowak, E., Martin, F., George, S., Conrad, K., Küpper, J.-H.Bacterial production and purification of paraneoplastic neurological syndrome autoantigen Ma2.

12th Dresden Symposium on Autoantibodies, September 2015, Dresden, Germany

Talk and Poster: George, S., Paulick, S., Knütter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Expression of nicotinic acetylcholine receptor subunits in HEp-2 cells for immunodetection of autoantibody specificities in sera from Myasthenia gravis patients.

Poster: George, S., Paulick, S., Knütter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Indirect immunofluorescence assay on fixed HEp-2 M4 cells for routine diagnostics of anti muscle-specific kinase autoantibodies in Myasthenia gravis.

Research Workshop Health Campus Brandenburg, October 2015, Potsdam, Germany

Poster: George, S.,  Rentzsch, J., Vanek, M., Roggenbuck, D., Conrad, K., Küpper, J.-H.Expression of nicotinic acetylcholine receptor subunits in HEp2 cells for immunodetection of autoantibody specificity of sera from Myasthenia gravis patients.

Poster: George, S., Paulick, S., Knütter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis.

Poster: Herzog, N., Hansen, M., Miethbauer, S., Schmidtke, K.-U., Anderer, U., Lupp, A., Sperling, S., Seehofer, D., Damm, G., Scheibner, K., Küpper, J.-H.Primary-like Human Hepatocytes Genetically Engineered to Obtain Proliferation Competence Display Hepatic Differentiation Characteristics in Monolayer and Organotypical Spheroid Cultures.

Poster: Herzog, N., Katzenberger, N., Martin, F., Schmidtke, K.-U., Küpper, J.-H.Generation of cytochrome P450 3A4-overexpressing HepG2 cell clones for standardization of hepatocellular testosterone 6 beta-hydroxylation activity.

Annual Meeting of the German Society for Clinical Microcirculation and Hemorheology, November 2015, Regensburg, Germany

Talk: George, S., Roggenbuck, D., Conrad, K., Küpper, J.-H. Sensitive immunodetection of muscle-specific kinase in fixed HEp-2 M4 cells for routine diagnostics of Myasthenia gravis.

Poster: Herzog, N., Katzenberger, N., Martin, F., Steinbrecht, S., Schmidtke, K.-U., Küpper, J.-H. Generation of cytochrome P450 3A4-overexpressing HepG2 cell clones for standardization of hepatocellular testosterone 6β-hydroxylation activity.

Poster: von Auw, N., George, S., Roggenbuck, D., Conrad, K., Küpper, J.-H.Entwicklung eines zellbasierten Assays zum diagnostischen Screening von Myasthenia gravis Patientenseren auf LRP4 Autoantikörper.

Poster: George, S., Rentzsch, J., Vanek, M., Roggenbuck, D., Conrad, K., Küpper, J.-H.Expression of nicotinic acetylcholine receptor subunits in HEp2 cells for immunodetection of autoantibody specificity of sera from Myasthenia gravis patients.

Annual Meeting of the German Society for Clinical Microcirculation and Hemorheology, November 2014, Schwenningen, Germany

Talk: George, S., Georgi, M., Roggenbuck, D., Conrad, K., Küpper J.-H.Targeting of cell membrane proteins to Golgi apparatus, mitochondria or endoplasmic reticulum: A strategy for cell-based multiplex diagnostics of autoimmune diseases.

Talk: George, S., Paulick, S., Knutter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis.

Poster: Katzenberger, N., Herzog, N., Kade, S., Martin, F., Schmidtke, K.-U., Küpper, J.-H.Biotransformation in HepG2 cells genetically engineered to overexpress liver phase I enzymes.

Poster: Kade, S., Herzog, N., Schmidtke, K.-U., Küpper, J.-H.Chronic ethanol treatment reduces glutathione regeneration capacity in HepG2 cells.

Poster: Herzog, N., Hansen, M., Kade, S., Miethbauer, S., Schmidtke, K.-U., Lupp, A., Damm, G., Scheibner, K., Küpper, J.-K.Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.