15th Dresden Symposium on Autoantibodies, September 2021, Dresden, Deutschland

Poster: Köhler, S., Locke, L., Kammerer, S., Herzog, N., Schulz, C., George, S., Sowa, M., Röber, N., Conrad, K., Roggenbuck, D., Küpper, J.-H. Lentivirus-mediated generation of autoantigen-overexpressing human cell lines for immunofluorescence-based diagnostics of autoimmune diseases.

Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, November 2019, Braunschweig, Deutschland

Vortrag: Schulz, C., Kammerer, S.,Küpper, J.-H. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.

Vortrag: Steinbrecht, S., Thiessen, M., Schmidke, K.-U., Kiebist, J., Kammerer, S., Scheibner, K., Küpper, J.-HEnzymatic synthesis of cyclophosphamide metabolites by an unspecific peroxygenase for toxicological studies on human cancer cells.

International Conference on Cytochrome P450 (ICCP450), Juni 2019, Brisbane, Australien

Poster: Steinbrecht, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Kammerer, S., Küpper, J.-H.Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4.

Ten Years Doctoral Program of Medical Science, November 2018, Medizinische Universität Graz, Österreich

Alumnipräsentation: Kammerer, S.  From Graz to Senftenberg via Berlin.

6th Eurosummer School on Biorheology & Symposium on Micro- and Nanomechanics and Mechanobiology of Cells, Tissues and Systems, August 2018, Varna, Bulgarien

Vortrag: Steinbrecht, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Kammerer, S., Küpper, J.-H.Metabolic activity testing underestimates acute cytotoxicity of CPA as revealed by CYP overexpressing HepG2 cell clones.

Vortrag: Kammerer, S.,Steinbrecht, S., Küpper, J.-H. Optimized culture conditions of the human proliferative liver cell line HepaFH3 for toxicity studies.

International Biotech Innovation Days (IBID), Mai 2018, Senftenberg, Deutschland

Vortrag: Steinbrecht, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Kammerer, S., Küpper, J.-H.Metabolic activity testing underestimates acute cytotoxicity of cyclophosphamide as revealed by cytochrome P450 overexpressing human hepatoma cell clones.

Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, Juni 2018, Neubrandenburg, Deutschland

Vortrag: Kammerer, S.,Steinbrecht, S., Küpper, J.-H.Optimierung von Kulturbedingungen der teilungsfähigen humanen Leberzelllinie HepaFH3 für Toxizitätsuntersuchungen.

Vortrag: Nowak, E., Kammerer, S., Küpper, J.-H.Etablierung eines Kokultur-Systems von Tumor- und Leberzellen für Wirksamkeits- und Toxizitätsuntersuchungen von Krebstherapeutika unter Berücksichtigung des First-Pass-Effekts.

Vortrag: Steinbrecht, S.,Kammerer, S., König, R., Schmidtke, K.-U., Herzog, N., Scheibner, K., Krüger-Genge, A., Jung, F., Küpper, J.-H.Metabolic activity testing underestimates acute cytotoxicity of cyclophosphamide as revealed by cytochrome P450 overexpressing human hepatoma cell clones.

Vortrag: Haileka, V., George, S., Steinbrecht, S., Küpper, J.-H.Metabolic activity of Colon Carcinoma Cell lines treated with Cyclophosphamide.

Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, Juni 2017, Greifswald, Deutschland

Vortrag: von Auw, N., George, S., Schmidtke, K.-U., Küpper, J.-H.Flow cytometry analyses for optimization of co-transfection efficiencies of plasmid constructs into mammalian cell lines.

Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, November 2016, Main, Deutschland

Vortrag: Steinbrecht, S., Herzog, N., Schmidtke, K.-U., Scheibner, K., Küpper, J.-H.Human CYP450 2C19 overexpressing HepG2 cell clone for drug testing.

Poster: Herzog, N., Katzenberger, N., Steinbrecht, S., Schmidtke, K.-U., Scheibner, K., Küpper, J.-H.Adaptation of human CYP450 3A4 overexpressing hepatoma cell line HepG2 to endothelial cell culture medium.

Poster: George, S., Rödiger, S., Schröder, C., Knaut, M., Küpper, J.-H.Development of multiplex PCR systems for expression profiling of human cardiomyocytes induced to proliferate by lentivirus transduction of upcyte genes.

Poster: Nowak, E., Martin, F., George, S., Conrad, K., Küpper, J.-H.Bacterial production and purification of paraneoplastic neurological syndrome autoantigen Ma2.

12th Dresden Symposium on Autoantibodies, September 2015, Dresden, Deutschland

Vortrag und Poster: George, S., Paulick, S., Knütter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Expression of nicotinic acetylcholine receptor subunits in HEp-2 cells for immunodetection of autoantibody specificities in sera from Myasthenia gravis patients.

Poster: George, S., Paulick, S., Knütter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Indirect immunofluorescence assay on fixed HEp-2 M4 cells for routine diagnostics of anti muscle-specific kinase autoantibodies in Myasthenia gravis.

Forschungsworkshop Gesundheitscampus Brandenburg, Oktober 2015, Potsdam, Deutschland

Poster: George, S.,  Rentzsch, J., Vanek, M., Roggenbuck, D., Conrad, K., Küpper, J.-H.Expression of nicotinic acetylcholine receptor subunits in HEp2 cells for immunodetection of autoantibody specificity of sera from Myasthenia gravis patients.

Poster: George, S., Paulick, S., Knütter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis.

Poster: Herzog, N., Hansen, M., Miethbauer, S., Schmidtke, K.-U., Anderer, U., Lupp, A., Sperling, S., Seehofer, D., Damm, G., Scheibner, K., Küpper, J.-H.Primary-like Human Hepatocytes Genetically Engineered to Obtain Proliferation Competence Display Hepatic Differentiation Characteristics in Monolayer and Organotypical Spheroid Cultures.

Poster: Herzog, N., Katzenberger, N., Martin, F., Schmidtke, K.-U., Küpper, J.-H.Generation of cytochrome P450 3A4-overexpressing HepG2 cell clones for standardization of hepatocellular testosterone 6 beta-hydroxylation activity.

Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, November 2015, Regensburg, Deutschland

Vortrag: George, S., Roggenbuck, D., Conrad, K., Küpper, J.-H. Sensitive immunodetection of muscle-specific kinase in fixed HEp-2 M4 cells for routine diagnostics of Myasthenia gravis.

Poster: Herzog, N., Katzenberger, N., Martin, F., Steinbrecht, S., Schmidtke, K.-U., Küpper, J.-H. Generation of cytochrome P450 3A4-overexpressing HepG2 cell clones for standardization of hepatocellular testosterone 6β-hydroxylation activity.

Poster: von Auw, N., George, S., Roggenbuck, D., Conrad, K., Küpper, J.-H.Entwicklung eines zellbasierten Assays zum diagnostischen Screening von Myasthenia gravis Patientenseren auf LRP4 Autoantikörper.

Poster: George, S., Rentzsch, J., Vanek, M., Roggenbuck, D., Conrad, K., Küpper, J.-H.Expression of nicotinic acetylcholine receptor subunits in HEp2 cells for immunodetection of autoantibody specificity of sera from Myasthenia gravis patients.

Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, November 2014, Schwenningen, Deutschland

Vortrag: George, S., Georgi, M., Roggenbuck, D., Conrad, K., Küpper J.-H.Targeting of cell membrane proteins to Golgi apparatus, mitochondria or endoplasmic reticulum: A strategy for cell-based multiplex diagnostics of autoimmune diseases.

Vortrag: George, S., Paulick, S., Knutter, I., Röber, N., Hiemann, R., Roggenbuck, D., Conrad, K., Küpper, J.-H.Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis.

Poster: Katzenberger, N., Herzog, N., Kade, S., Martin, F., Schmidtke, K.-U., Küpper, J.-H.Biotransformation in HepG2 cells genetically engineered to overexpress liver phase I enzymes.

Poster: Kade, S., Herzog, N., Schmidtke, K.-U., Küpper, J.-H.Chronic ethanol treatment reduces glutathione regeneration capacity in HepG2 cells.

Poster: Herzog, N., Hansen, M., Kade, S., Miethbauer, S., Schmidtke, K.-U., Lupp, A., Damm, G., Scheibner, K., Küpper, J.-K.Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.