12767 - Point of Care Diagnostic Modulübersicht

Module Number: 12767
Module Title:Point of Care Diagnostic
  Point-of-Care-Diagnostik
Department: Faculty 2 - Environment and Natural Sciences
Responsible Staff Member:
  • Dr. rer. nat. Hansen, Barbara
Language of Teaching / Examination:English
Duration:1 semester
Frequency of Offer: Every winter semester
Credits: 5
Learning Outcome:The module teaches the basics of point of care diagnostics / point of care analysis, molecular diagnostics, biochip technology and their techniques. The students will be able to explain the term point of care testing using concrete examples and are introduced in scientific thinking. The module teaches special abilities and knowledge in the field of bioanalytics for biotechnologically and biochemically oriented students.After successful participation in the module students are able to explain and apply scientific principles as well as specialised and in-depth knowledge. -They can develop independent ideas and concepts to solve scientific and professional problems.
Contents:In the lecture different bioanalytical detection techniques will be presented, whereby the biosensorics occupy a partly higher importance. Important combinations of biomolecules with sensors and their bioanalytical application are discussed.

On the basis of practice-relevant examples, the development of individual biosensors will be presented, as well as their limitations and solutions for optimization discussed. Other topics include biochip technology, molecular diagnostics, point of care testing (POCT), on-site analysis and nanobiotechnology.

  • Enzymatic sensor concepts and selected examples (glucose oxidase enzyme electrode)
  • DNA Sensors
  • Immunosensors
  • Cell-based biosensors
  • In vivo Biosensors
  • Disposable biosensors in point-of-care applications: concepts and fabrication
  • Clinical applications: blood gas analyses, coagulation diagnosis, cardiovascular diseases
 
Current publications in the field of point-of-care diagnostics and on-site analysis will be presented and discussed with regard to a point-of-care application.
Recommended Prerequisites:none
Mandatory Prerequisites:none
Forms of Teaching and Proportion:
  • Lecture / 2 Hours per Week per Semester
  • Seminar / 1 Hours per Week per Semester
  • Self organised studies / 105 Hours
Teaching Materials and Literature:POCT-Patientennahe Labordiagnostik, P. Luppa, R. Junker (eds), ISBN 978-3-662-54195-1, ISBN 978-3-662-54196-8 (ebook)
 
Publications:
  • Khan et al, Diagnostics 2017, 7, 39; doi: 10.3390/diagnostics7030039
  • Krampa et al., Diagnostics 2017,7, 54; doi: 10.3390/diagnostics/7030054
  • Mashamba-Thompson et al, Diagnostics 2016,6,31;doi: 10.3390/diagnostics6030031
Module Examination:Final Module Examination (MAP)
Assessment Mode for Module Examination:Written Examination (120 min)
Evaluation of Module Examination:Performance Verification – graded
Limited Number of Participants:None
Part of the Study Programme:
  • Abschluss im Ausland / Biotechnologie / keine PO
  • Master (applied) / Biotechnology / PO 2018
  • Master (applied) - Extended Semester / Biotechnology / PO 2018
  • Abschluss im Ausland / Medizininformatik / keine PO
Remarks:"Recommended Placement in the Study Plan"
  • Biotechnology (Master of Science, 3 Semester Version): Master 1st year course
  • Biotechnology (Master of Science, 4 Semester Version): Master 2nd year course

"Responsible Staff Member"

  1. Prof. Frank Hufert (no)
  2. Dr. Gregory Dame (no)
Module Components:
  • Lecture "Point of Care Diagnostic"
  • Seminar "Point of Care Diagnostic"
  • Examination "Point of Care Diagnostic"
Components to be offered in the Current Semester: