14336 - Introduction to Bioinformatics Modulübersicht

Module Number: 14336
Module Title:Introduction to Bioinformatics
  Einführung in die Bioinformatik
Department: Faculty GW - Faculty of Health Sciences Brandenburg
Responsible Staff Member:
  • Prof. Dr. rer. nat. Schliep, Alexander
Language of Teaching / Examination:English
Duration:1 semester
Frequency of Offer: Every winter semester
Credits: 6
Learning Outcome:After successfully completing the module, students have acquired an overview of the fundamentals of bioinformatics. This includes an introduction to relevant molecular processes, scientific instruments to investigate these processes, and the data generated by them. For central computational problems, students are able to discuss advantages and disadvantages of statistical and basic algorithmic approaches, respectively adapt them to specific biological questions. Students are able to analyze specific biological data using
appropriate software libraries for Python.
Contents:The focus will be on the basics of the following areas:
  • An introduction to molecular biology including relevant scientific instruments and the Omics-data generated by them.
  • Pair-wise and multiple sequence alignments, seed-and-extend approaches, and genome indexes
  • Evolutionary models and phylogenetic trees
  • Signals in sequences: identification of motifs
  • Assembly of genomes and transcriptomes
  • Gene expression analysist
Recommended Prerequisites:Good knowledge of discrete probability, algorithms and data structures at the undergraduate level. Advanced knowledge of programming in Python and the Linux command line.
Mandatory Prerequisites:None
Forms of Teaching and Proportion:
  • Lecture / 2 Hours per Week per Semester
  • Exercise / 2 Hours per Week per Semester
  • Study project / 30 Hours
  • Self organised studies / 90 Hours
Teaching Materials and Literature:
  • Biological Sequence Analysis. Durbin, Eddy, Krogh, Mitchison (1998)
  • Statistical Methods in Bioinformatics. Ewens and Grant (2005)
  • Review and Original Research Articles
Module Examination:Prerequisite + Final Module Examination (MAP)
Assessment Mode for Module Examination:Prerequisite:
  • passed exercises:
    A passing grade in 60% of the problems sets will be required to be admitted to the module examination.
Final Module Examination:
  • Written examination, 120 min. OR
  • Oral examination, 30-45 min.
In the first lecture it will be announced whether the examination will organized in written or oral form.
Evaluation of Module Examination:Performance Verification – graded
Limited Number of Participants:None
Part of the Study Programme:
  • Master (research-oriented) / Artificial Intelligence / PO 2022
  • Master (research-oriented) / Informatik / PO 2008
Remarks:None
Module Components:
  • Lecture: Introduction to Bioinformatics
  • Accompanying exercise
  • Related examination
Components to be offered in the Current Semester: