Modeling, simulation and optimization of the internal structure of components according to the biological model of bone formation

Author: MA Alexander Melcher

Second supervisor: PD Dr.-Ing. habil. Thomas Hinze from Chair for Bioinformatic at the Matthias-Schleiden-Institut, Fakulty for Biosciences, Friedrich-Schiller-Universität Jena

The formation of stress lines in the bone substance is based on mechanisms that act during the bone growth. There are two major processes of bone construction performed by osteoblasts and bone degradation performed by osteoclasts. This steady buildup and degradation causes the bone structure to develop. However, there are many factors that differentiate bone from a common material, such as steel or concrete. The master thesis develops a system for the construction of a spatial structure modeled on the growth of the bone. This has been investigated by means of simulation studies on its carrying capacity and further optimized via the developed system implemented with the help of Rhino 3D, Grasshopper, Karamba and own scripts.

The paper was accepted at the 19th International Conference on Membrane Computing (CMC19) as a paper titled "Construction of Stable and Lightweight Technical Structures Inspired by Ossification of Bones using Osteogenetic P Systems" and was awarded the CMC19 Best Paper Award.