Masterarbeit

Jens Schneider (2018): Site-directed mutagenesis of Proteasome Activator 28γ (PA28γ): Molecular mimicry of PA28γ acetylation (K195Q) modulates assembly and 20S proteasome activity

Meike Rosanski (2017): PSME3 gene targeting in cancer cells using a CRISPR/Cas9 system to study the anti-apoptotic mechanism of PA28γ

Marcel Schlecht (2016): Functional analysis of PA28γ in MCF-7 breast cancer cells by overexpression & CRISPR-Cas9 mediated gene silencing

Andrea Krause (2011): Production and affinity purification of in vivo citrullinated RA autoantigens in baculovirus infected insect cells

Josephine Tabea Tauer (2008): In vitro citrullination of proteins: Implications on the diagnosis of autoimmune diseases

Bachelorarbeit

Gina Göritz (2023): Proteasome Binding Affinities of Variant PA28γ Heptamers Examined via Microscale Thermophoresis

Theresa Birghan (2022): Untersuchung der Rolle des Proteasom-Aktivators 28γ (PA28γ) auf Proliferation, Migration und Apoptose in humanen embryonalen Nierenzellen (HEK293 Zellen)

Paula Piater (2022): Mutagenese, Aufreinigung und Charakterisierung funktioneller Varianten des Proteasom-Aktivators PA28γ

Tim Dzewas (2018): CRISPR/Cas9 mediated Knockout of Proteasome Inhibitor PI31

Inge Schwedt (2017): Klonierung und Expression humaner Procaspase-3 in Escherichia coli

Julia Engelmann (2013): Biochemische Analyse von mutierten Varianten des anti-apoptotischen Proteasomaktivators 28γ in B8-Mausfibroblasten

Stefanie Trapp (2012): Anti-apoptotic mechanism of the proteasome activator PA28γ: functional characterization of mutants in B8 mouse fibroblasts

Juliane Scholz (2012): Cloning, expression and functional characterization of human PAD isoforms relevant for functions in rheumatoid arthritis

Maria König (2010): Proteasome Aktivator 28γ: Modulation des proteasomalen in vitro Abbaus des Zellzyklusinhibitors p21

Dominique Vogt (2009): Entwicklung eines ELISA Prototypen zum Nachweis von spezifischen Autoantikörpern gegen den Proteasomaktivator PA28γ

BRIDGE to Master

Berfinsu Kaya (2023): Expression and Characterization of Proteasome Activator PA28 Gamma Mutant

Muthu Kumaran Parthiban (2023): In vitro analysis of missense mutations and characterization of PA28γ

Fatemehsadat Toghraie (2022): Transfection of HEK293 Knockout and Wild-type Cells for Transient and Stable Expression of PA28γ

Harith Ekal (2019): The role of the proteasome activator 28γ (PA28γ) in apoptosis and DNA Repair

Praxissemester

Anjana Khadka (2020): Purification and in vitro characterization of modified proteasome activator PA28ү

Shiva Raj Tripathi (2020): Purification and in-vitro characterisation of proteasome activator PA28ɤ mutants

Alexander Heine (2017): Isolierung von humanem PA28γ für Proteasom Aktivierungs Assays

Julia Engelmann (2012): Nachweis von nukleären, cytosolischen und membrangebundenen Antigenen in SF21 Insektenzellen, Practical Term Report