The project is a cooperation between the Berlin PolyAn GmbH and the BTU Cottbus-Senftenberg and is financed by the European Union (ERDF) and the State of Brandenburg (ILB). It is a three-year project that started on June 01, 2017 and will end on May 31, 2020. The aim is the development of multiparametric detection methods that can be marketed by PolyAn GmbH. The basis are small fluorescence-coded submicron and nanoparticles whose production is specialized in PolyAN GmbH. First of all, strategies are developed at the Senftenberg site in the laboratories of the Institute for Biotechnology that allow the coupling of antibodies with the particles. Then proof-of-concepts are developed for the following detection methods:
1. Development of an agglutination assay that allows the serotyping of bacteria.
2. Development of a "lateral flow assay" that can detect IgM antibodies specific for rheumatoid arthritis.
3. Development of a cytokine assay. In addition, the biocompatibility of submicroparticles and nanoparticles with different cell lines is investigated.